Semaphorin-6A Antibodies

AND Sema6a ELISA kits, Semaphorin-6A Proteins

Many biological assays use antibodies to detect Semaphorin-6A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Semaphorin-6A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Semaphorin-6A antibodies...

We validate the specificity of these antibodies to Semaphorin-6A by testing them on tissues known to express Sema6a positively and negatively. Browse below to find the Sema6a antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sema6a Infographic by Boster Bio

All Sema6a Products

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Product

Figures

Specificity

Applications

Price

Mouse SEMA6A/Semaphorin-6A ELISA Kit PicoKine®

9 Q&As

Mouse

ELISA

$499
Cat # EK2056
96 wells/kit, with removable strips.

Rat SEMA6A/Semaphorin-6A ELISA Kit PicoKine®

9 Q&As

Rat

ELISA

$499
Cat # EK2057
96 wells/kit, with removable strips.

Anti-SEM6A SEMA6A Antibody

Human, Mouse

ELISA, WB

$380
Cat # A06967
100ul

Anti-Sema6A Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IHC, WB

$370
Cat # A06967-1
100 μg/vial

SEMA6A (NM_020796) Human Over-expression Lysate

Human

$960
Cat # LS057556
100 µg

Sema6a Overview

Facts about Semaphorin-6A.

Semaphorin-6A (Sema6a)

Cell surface receptor for PLXNA2 that plays an significant role in cell-cell signaling. Required for normal granule cell migration in the developing cerebellum.

Promotes reorganization of the actin cytoskeleton and plays an important role in axon guidance in the developing central nervous system. Can act as repulsive axon guidance cue.

Gene Information

Mouse
Gene Name:	Sema6a
Uniprot:	O35464
Entrez:	20358

Family

Belongs to:

semaphorin family

Alternative Names

KIAA1368HT018; sema domain, transmembrane domain (TM), and cytoplasmic domain, (semaphorin) 6A; Sema VIA; SEMA; Sema6A; SEMA6A1; SEMA6A-1; Semaphorin 6A; semaphorin 6A-1; Semaphorin VIA; semaphorin-6A; semaphorin-6A-1; SEMAQ; VIA

Molecular Weight

Mass (kDA):
114.433 kDA

Genomic Context


Mouse

Location:	18\|18 C
Sequence:	18;

Tissue Specificity

Particularly high levels in spinal cord, cerebellum, metencephalon, superior and inferior colliculus, diencephalon, olfactory bulb and eye.

Diseases

Nervousness
Tumor Angiogenesis
Neoplasms
Malignant Neoplasms
Pathologic Neovascularization
Tissue Adhesions
Crest Syndrome
Kidney Neoplasm
Carcinoma
Renal Cell Carcinoma
Conventional (clear Cell) Renal Cell Carcinoma
Malnutrition

Brain Ischemia
Fracture Of First Cervical Vertebra
Muscular Fasciculation
Glaucoma, Open-angle
Exudative Age-related Macular Degeneration
Acute-phase Reaction
Dermatopathic Lymphadenopathy

Pathways

Axon Guidance
Cell Migration
Angiogenesis
Cell Adhesion
Cell Motility
Visual Perception
Cell Proliferation
Cell Death
Pathogenesis
Innervation
Rna Interference
Neural Tube Closure
Response To Wounding

Somal Translocation
Brain Development
Proteolysis
Myelination
Cerebellum Development
Axon Extension
Chemotaxis

PTMs

Phosphorylation

Ubiquitination

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sema6a

References

PMID: 10993894 by Klostermann A., et al. The orthologous human and murine semaphorin 6A-1 proteins (SEMA6A- 1/Sema6A-1) bind to the enabled/vasodilator-stimulated phosphoprotein- like protein (EVL) via a novel carboxyl-terminal zyxin-like domain.

PMID: 9204478 by Zhou L., et al. Cloning and expression of a novel murine semaphorin with structural similarity to insect semaphorin I.