SART1 Antibodies

AND SART1 ELISA kits, SART1 Proteins

Many biological assays use antibodies to detect SART1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SART1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SART1 antibodies...

We validate the specificity of these antibodies to SART1 by testing them on tissues known to express SART1 positively and negatively. Browse below to find the SART1 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SART1 Infographic by Boster Bio

All SART1 Products

Product

Figures

Specificity

Applications

Price

Anti-SART1 Antibody

Human, Mouse, Rat

IP, IHC, WB

$405
Cat # A05414
100ul

SART1 (NM_005146) Human Over-expression Lysate

Human

$628
Cat # LS009092
100 µg

Anti-SART1 Antibody Picoband™

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A05414-1
100 μg/vial

SART1 Overview

Facts about U4/U6.U5 tri-snRNP-associated protein 1.

SART1 3D structure. Source: alphafold

U4/U6.U5 tri-snRNP-associated protein 1 (SART1)

Plays a role in mRNA splicing as a component of the U4/U6-U5 tri-snRNP, one of the building blocks of the spliceosome. May also bind to DNA.

Gene Information

Human
Gene Name:	SART1
Uniprot:	O43290
Entrez:	9092

Family

Belongs to:

SNU66/SART1 family

Alternative Names

Allergen Hom s 1; Ara1; HAF; HOMS1; hSART-1; hSnu66; hypoxia-associated factor; IgE Autoantigen; MGC2038; SART1; SART-1; SART1(259) protein; SART1(800) protein; SART1259; small nuclear ribonucleoprotein 110kDa (U4/U6.U5); SNRNP110; SNU66 homolog; Snu66; squamous cell carcinoma antigen recognised by T cells; Squamous cell carcinoma antigen recognized by T cells 1; squamous cell carcinoma antigen recognized by T cells; U4/U6.U5 tri-snRNP-associated 110 kDa protein; U4/U6.U5 tri-snRNP-associated protein 1

Molecular Weight

Mass (kDA):
90.255 kDA

Genomic Context


Human

Location:	11q13.1
Sequence:	11; NC_000011.10 (65961727..65980137)

Tissue Specificity

Ubiquitously expressed.

Subcellular Localizations

Nucleus. Found in the nucleus of mitogen-activated peripheral blood mononuclear cells (PBMCs), tumor cells, or normal cell lines, but not in normal tissues except testis and fetal liver or in unstimulated PBMCs, suggesting preferential expression in proliferating cells.

Diseases

Neoplasms
Malignant Neoplasms
Carcinoma
Malignant Squamous Cell Neoplasm
Malignant Paraganglionic Neoplasm
Adenocarcinoma
Melanoma
Malignant Neoplasm Of Breast
Glioma
Hypoxia
Mammary Neoplasms
Esophageal Neoplasms
Hepatitis

Colorectal Neoplasms
Neoplasm Metastasis
Kidney Neoplasm
Mouth Neoplasms
Tumor Angiogenesis
Renal Cell Carcinoma
Liver Carcinoma

Interacting Proteins

HSF2BP
SNW1
SUMO1
SUMO3
UBL5

Pathways

Immune Response
Reverse Transcription
Translation
Transposition
Localization
Angiogenesis
Circadian Rhythm
Mitosis
Interferon-gamma Production
Translation Reinitiation
Humoral Immune Response
Cell Cycle Arrest

Cell Division
Drug Resistance
Cell Cycle
Cell Death
Mrna Processing
Cell Growth
Nuclear Import

PTMs

Sumoylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SART1

References

PMID: 9449708 by Shichijo S., et al. A gene encoding antigenic peptides of human squamous cell carcinoma recognized cytotoxic T lymphocytes.

PMID: 11350945 by Makarova O.V., et al. The 65 and 110 kDa SR-related proteins of the U4/U6*U5 tri-snRNP are essential for the assembly of mature spliceosomes.