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- Table of Contents
Facts about Synaptotagmin-10.
Not included in Ca(2+)-dependent synaptic vesicle exocytosis (PubMed:21496647). Acts through Ca(2+) and phospholipid binding to the C2 domain: Ca(2+) induces binding of the C2-domains to phospholipid membranes and to assembled SNARE- complexes; both actions contribute to triggering exocytosis (By similarity).
Mouse | |
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Gene Name: | Syt10 |
Uniprot: | Q9R0N4 |
Entrez: | 54526 |
Belongs to: |
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synaptotagmin family |
Synaptotagmin-10
Mass (kDA):
59.019 kDA
Mouse | |
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Location: | 15|15 E3 |
Sequence: | 15; |
Highly expressed in the olfactory bulb.
PMID: 10531343 by Fukuda M., et al. Conserved N-terminal cysteine motif is essential for homo- and heterodimer formation of synaptotagmins III, V, VI, and X.
PMID: 10531344 by Fukuda M., et al. A novel alternatively spliced variant of synaptotagmin VI lacking a transmembrane domain. Implications for distinct functions of the two isoforms.