Synaptophysin Antibodies

AND SYP ELISA kits, Synaptophysin Proteins

Many biological assays use antibodies to detect Synaptophysin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Synaptophysin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Synaptophysin antibodies...

We validate the specificity of these antibodies to Synaptophysin by testing them on tissues known to express SYP positively and negatively. Browse below to find the SYP antibody that suites your experiment. We have 10 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SYP Infographic by Boster Bio

All SYP Products

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Product

Figures

Specificity

Applications

Price

Anti-Synaptophysin/SYP Antibody Picoband®

3 Citations 15 Q&As

Human, Mouse, Rat

$370
Cat # PB9409
100 μg/vial

Anti-Synaptophysin Syp Antibody (Monoclonal, SVP-38)

5 Citations 18 Q&As

Human, Rat

IHC, WB

$370
Cat # MA1091
100 μg/vial

Anti-Synaptophysin SYP Rabbit Monoclonal Antibody

2 Citations 16 Q&As

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # M05049-1
100 μl

Anti-Synaptophysin SYP Rabbit Monoclonal Antibody

2 Citations 16 Q&As

Human, Mouse, Rat

Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # M05049
100 μl

Anti-Synaptophysin SYP Rabbit Monoclonal Antibody, Clone#RM258

1 Citations 16 Q&As

Human

IHC, WB

$431
Cat # M05049-2
100uL

Synaptophysin Colorimetric Cell-Based ELISA Kit

Human, Mouse, Rat

ELISA

$480
Cat # EKC1555
1 kit, containing one 96-well plate and all necessary reagents

Anti-SYP/Synaptophysin Antibody Picoband® (monoclonal, 3G12)

2 Citations 4 Q&As

Mouse, Rat

$370
Cat # M05049-3
100 μg/vial

Anti-Synaptophysin/SYP Picoband® Antibody

8 Citations

Human, Mouse, Rat

IF, IHC, ICC, WB

$370
Cat # A05049
100 μg/vial

Anti-SYP Antibody (C-term)

Human, Mouse

$299
Cat # M05049-4
50 µl

Synaptophysin (SYP) (NM_003179) Human Over-expression Lysate

Human

$628
Cat # LS006855
100 µg

SYP Overview

Facts about Synaptophysin.

SYP 3D structure. Source: alphafold

Synaptophysin (SYP)

Possibly involved in structural functions as organizing other membrane components or in targeting the vesicles to the plasma membrane. Involved in the regulation of short-term and long-term synaptic plasticity (By similarity).

. .

Gene Information

Human
Gene Name:	SYP
Uniprot:	P08247
Entrez:	6855

Family

Belongs to:

synaptophysin/synaptobrevin family

Alternative Names

Major synaptic vesicle protein p38; MRX; MRXSYP; Synaptophysin; SYP

Molecular Weight

Mass (kDA):
33.845 kDA

Genomic Context


Human

Location:	Xp11.23
Sequence:	X; NC_000023.11 (49187815..49200193, complement)

Tissue Specificity

Characteristic of a type of small (30-80 nm) neurosecretory vesicles, including presynaptic vesicles, but also vesicles of various neuroendocrine cells of both neuronal and epithelial phenotype.

Subcellular Localizations

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cell junction, synapse, synaptosome.

Diseases

Neoplasms
Alzheimer's Disease
Carcinoma
Brain Injuries
Posttransfusion Purpura
Malignant Neoplasms
Nervousness
Impaired Cognition
Carcinoma, Neuroendocrine
Tissue Adhesions
Hyperplasia
Janiceps

Memory Impairment
Cell Transformation, Neoplastic
Liver Carcinoma
Metaplastic Cell Transformation
Hypertrophy
Insulin Resistance
Neuroblastoma

Pathways

Localization
Biofilm Formation
Transport
Aging
Secretion
Cell Proliferation
Cell Adhesion
Regeneration
Exocytosis
Pathogenesis
Glucose Transport
Synaptic Transmission
Cell Growth

Cell Activation
T Cell Activation
Glucose Homeostasis
Swimming
Cell Differentiation
Neurogenesis
Virulence

PTMs

Phosphorylation
Dephosphorylation
Nitration

Cleavage
Glycosylation
Acetylation

Ribosylation

Research Areas

Membrane Vesicle Markers
Neuronal Cell Markers
Neuroscience
Neurotransmission
Stem Cell Markers

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SYP

References

PMID: 3120152 by Suedhof T.C., et al. The cDNA and derived amino acid sequences for rat and human synaptophysin.

PMID: 1975480 by Oezcelik T., et al. Synaptophysin: structure of the human gene and assignment to the X chromosome in man and mouse.

11 Publications of Boster Synaptophysin Antibodies & ELISA Kits

PubMed ID: 10.1167/iovs.09-4504, Generation of Retinal Ganglion–like Cells from Reprogrammed Mouse Fibroblasts
PubMed ID: 10.1080/00207454.2017.1387115, Effects of spontaneous recurrent seizures on cognitive function via modulation o...
PubMed ID: 10.1016/j.tox.2017.04.001, The induction of cytochrome P450 2E1 by ethanol leads to the loss of synaptic pr...
PubMed ID: 10.1016/j.neulet.2008.02.058, RETRACTED: Effect of ephedrine on neuronal plasticity of hypoxic-ischemic brain ...
PubMed ID: 10.1016/j.brainres.2006.09.058, Catalpol increases hippocampal neuroplasticity and up-regulates PKC and BDNF in ...
PubMed ID: 10.1002/syn.20684, Abnormality of synaptic vesicular associated proteins in cerebral cortex and hip...
PubMed ID: 33335999, Jing M,Yi Y,Jinniu Z,Xiuli K,Jianxian W.Rehabilitation training improves nerve i...
PubMed ID: 33531914, Lin J,Hao C,Gong Y,Zhang Y,Li Y,Feng Z,Xu X,Huang H,Liao W. Effect of Tetramethy...
PubMed ID: 23271319, Li Xh, Xin X, Wang Y, Wu Jz, Jin Zd, Ma Ln, Nie Cj, Xiao X, Hu Y, Jin Mw. J Alzh...
PubMed ID: 25206583, Liu Y, Liang Z, Liu J, Zou W, Li X, Wang Y, An L. Neural Regen Res. 2013 Oct 15;...
PubMed ID: 24457043, Chen Y, Wei G, Nie H, Lin Y, Tian H, Liu Y, Yu X, Cheng S, Yan R, Wang Q, Liu Dh...

*More publications can be found for each product on its corresponding product page