SV2B Antibodies

AND SV2B ELISA kits, SV2B Proteins

Many biological assays use antibodies to detect SV2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SV2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SV2B antibodies...

We validate the specificity of these antibodies to SV2B by testing them on tissues known to express SV2B positively and negatively. Browse below to find the SV2B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SV2B Infographic by Boster Bio

All SV2B Products

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Product

Figures

Specificity

Applications

Price

Anti-SV2B Antibody

Human, Mouse, Rat

ELISA, WB

$380
Cat # A09577
100ul

SV2B (NM_014848) Human Over-expression Lysate

Human

$628
Cat # LS009899
100 µg

SV2B Overview

Facts about Synaptic vesicle glycoprotein 2B.

SV2B 3D structure. Source: alphafold

Synaptic vesicle glycoprotein 2B (SV2B)

Probably plays a role in the management of regulated secretion in neural and endocrine cells. .

Gene Information

Human
Gene Name:	SV2B
Uniprot:	Q7L1I2
Entrez:	9899

Family

Belongs to:

major facilitator superfamily

Alternative Names

FLJ30413; FLJ42732; HsT19680; KIAA0735HsT19680; SV2B; synaptic vesicle glycoprotein 2B; synaptic vesicle protein 2B homolog

Molecular Weight

Mass (kDA):
77.444 kDA

Genomic Context


Human

Location:	15q26.1
Sequence:	15; NC_000015.10 (91099588..91302565)

Subcellular Localizations

Cytoplasmic vesicle, secretory vesicle, synaptic vesicle membrane; Multi-pass membrane protein. Cytoplasmic vesicle, secretory vesicle, acrosome. Associated with synaptic-like microvesicles but not with insulin-containing vesicles in insulin-secreting cells of the pancreas (By similarity). Localizes to microvesicles in the pinealocytes. Localizes to the acrosome in spermatids (By similarity).

Diseases

Epilepsy
Malignant Neoplasms
Proteinuria Of Undiagnosed Cause
Kidney Diseases
Neoplasms
Adenocarcinoma
Atrophy
Prostatic Neoplasms
Tetanus
Nervousness
Malignant Neoplasm Of Prostate
Muscular Atrophy

Cholangiocarcinoma
Spinal Cord Injuries
Varicosity
Malignant Neoplasm Of Breast
Trinucleotide Repeat Expansion
Membranous Glomerulonephritis
Benign Prostatic Hypertrophy

Interacting Proteins

HSFY1

Pathways

Exocytosis
Synaptic Transmission
Synaptic Vesicle Exocytosis
Localization
Transport
Secretion
Glycosylation
Muscle Atrophy
Translation
Insulin Secretion
Cell Development
Aging
Regeneration

Cell Cycle
Cell Growth
Innervation
Regulation Of Synaptic Vesicle Exocytosis
Rna Interference
Regulation Of Synaptic Transmission
Transdifferentiation

PTMs

Glycosylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SV2B

References

PMID: 29649119 by Gustafsson R., et al. Crystal structure of botulinum neurotoxin A2 in complex with the human protein receptor SV2C reveals plasticity in receptor binding.