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Stxbp4 Antibodies
AND Stxbp4 ELISA kits, Stxbp4 Proteins
Many biological assays use antibodies to detect Stxbp4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Stxbp4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Stxbp4 antibodies...
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Stxbp4 Infographic by Boster Bio
All Stxbp4 Products
Product
Figures
Specificity
Applications
Price
Human
$960
Cat # LS252983
100 µg
Cat # LS252983
100 µg
Stxbp4 Overview
Facts about Syntaxin-binding protein 4.
Syntaxin-binding protein 4 (Stxbp4)
Plays a role in the translocation of transport vesicles in the cytoplasm to the plasma membrane. Inhibits the translocation of SLC2A4 from intracellular vesicles to the plasma membrane by STX4A binding and preventing the interaction between STX4A and VAMP2.
Stimulation with insulin disrupts the interaction with STX4A, resulting in increased levels of SLC2A4 at the plasma membrane. May also play a role in the regulation of insulin release by pancreatic beta cells after stimulation by glucose.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Stxbp4 |
| Uniprot: | Q9WV89 |
| Entrez: | 20913 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
FLJ16496; MGC50337; STX4-interacting protein; SynipMGC149829; syntaxin 4 interacting protein; Syntaxin 4-interacting protein; syntaxin binding protein 4; syntaxin-binding protein 4
Molecular Weight
Mass (kDA):
61.689 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 11|11 D |
| Sequence: | 11; |
Tissue Specificity
Detected in skeletal muscle, heart, testis, adipocytes and pancreatic islet cells.
Diseases
- Malignant Neoplasms
- Malignant Neoplasm Of Breast
- Brca2 Gene Mutation
- Malignant Squamous Cell Neoplasm
- Neoplasms
- Inflammation
- Mammary Neoplasms
- Tissue Adhesions
Pathways
- Transport
- Exocytosis
- Glucose Transport
- Plasma Membrane Fusion
- Response To Stress
- Insulin Secretion
- Synaptic Transmission
- Membrane Fusion
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Stxbp4
bosterbio.com/bosterbio-gene-info-cards/Stxbp4
References
PMID: 10394363 by Min J., et al. Synip: a novel insulin-regulated syntaxin 4-binding protein mediating GLUT4 translocation in adipocytes.
PMID: 12855681 by Saito T., et al. Syntaxin 4 and Synip (syntaxin 4 interacting protein) regulate insulin secretion in the pancreatic beta HC-9 cell.