STXBP3 Antibodies

AND STXBP3 ELISA kits, STXBP3 Proteins

Many biological assays use antibodies to detect STXBP3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STXBP3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STXBP3 antibodies...

We validate the specificity of these antibodies to STXBP3 by testing them on tissues known to express STXBP3 positively and negatively. Browse below to find the STXBP3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STXBP3 Infographic by Boster Bio

All STXBP3 Products

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Product

Figures

Specificity

Applications

Price

Anti-Syntaxin-binding protein 3 STXBP3 Antibody

Human, Mouse, Rat

IF, WB

$405
Cat # A08994
100ul

Munc18c (STXBP3) (NM_007269) Human Over-expression Lysate

Human

$628
Cat # LS006814
100 µg

STXBP3 Overview

Facts about Syntaxin-binding protein 3.

STXBP3 3D structure. Source: alphafold

Syntaxin-binding protein 3 (STXBP3)

Together with STX4 and VAMP2, may play a part in insulin-dependent movement of GLUT4 and in docking/fusion of intracellular GLUT4-containing vesicles with the cell surface in adipocytes. .

Gene Information

Human
Gene Name:	STXBP3
Uniprot:	O00186
Entrez:	6814

Family

Belongs to:

STXBP/unc-18/SEC1 family

Alternative Names

MUNC18-3; Munc18c; Platelet Sec1 protein; Protein unc-18 homolog 3; Protein unc-18 homolog C; PSP; STXBP3; syntaxin 4 binding protein; syntaxin binding protein 3; syntaxin-binding protein 3; SyntaxinBP3; Syntaxin-BP3; unc18-3; Unc-18C

Molecular Weight

Mass (kDA):
67.764 kDA

Genomic Context


Human

Location:	1p13.3
Sequence:	1; NC_000001.11 (108746674..108809523)

Tissue Specificity

Megakaryocytes and platelets.

Subcellular Localizations

Cytoplasm, cytosol. Cell membrane. In platelets, predominantly cytosolic. Low amounts membrane-associated.

Diseases

Insulin Resistance
Pancreatitis
Impaired Glucose Tolerance
Diabetes Mellitus
Insulin Sensitivity
Diabetes Mellitus, Non-insulin-dependent
Carcinoid Tumor
Malignant Neoplasms
Neurofibrillary Tangles
Brain Injuries
Acute Pancreatitis
Lipodystrophy

Traumatic Brain Injury
Atherosclerosis
Hermanski-pudlak Syndrome
Intestinal Neoplasms
Albinism, Oculocutaneous
Pancreatitis, Alcoholic
Obesity

Pathways

Transport
Secretion
Exocytosis
Glucose Transport
Vesicle Transport
Glucose Homeostasis
Insulin Secretion
Membrane Fusion
Vesicle Docking
Snare Complex Assembly
Cell Maturation
Plasma Membrane Fusion
Cell Division

Cognition
Hemostasis
Membrane Docking
Gastric Acid Secretion
Glycosylation
Synaptic Transmission
Protein Transport

PTMs

Phosphorylation

Biotinylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STXBP3

References

PMID: 8824310 by Gengyo-Ando K., et al. A murine neural-specific homolog corrects cholinergic defects in Caenorhabditis elegans unc-18 mutants.

PMID: 10194441 by Reed G.L., et al. Human platelets contain SNARE proteins and a Sec1p homologue that interacts with syntaxin 4 and is phosphorylated after thrombin activation: implications for platelet secretion.