STYX Antibodies

AND STYX ELISA kits, STYX Proteins

Many biological assays use antibodies to detect STYX, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STYX in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STYX antibodies...

We validate the specificity of these antibodies to STYX by testing them on tissues known to express STYX positively and negatively. Browse below to find the STYX antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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STYX Infographic by Boster Bio

All STYX Products

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Specificity

Applications

Price

STYX (NM_001130701) Human Recombinant Protein

$813
Cat # PROTQ8WUJ0
20 µg

STYX (NM_145251) Human Over-expression Lysate

Human

$628
Cat # LS006815
100 µg

STYX Overview

Facts about Serine/threonine/tyrosine-interacting protein.

STYX 3D structure. Source: alphafold

Serine/threonine/tyrosine-interacting protein (STYX)

Catalytically inactive phosphatase (PubMed:23847209). Acts as a nuclear anchor for MAPK1/MAPK3 (ERK1/ERK2) (PubMed:23847209).

Modulates cell-fate decisions and cell migration by spatiotemporal regulation of MAPK1/MAPK3 (ERK1/ERK2) (PubMed:23847209). By binding to the F-box of FBXW7, prevents the assembly of FBXW7 to the SCF E3 ubiquitin-protein ligase complex, and thereby inhibits degradation of its substrates (PubMed:28007894).

Gene Information

Human
Gene Name:	STYX
Uniprot:	Q8WUJ0
Entrez:	6815

Family

Belongs to:

protein-tyrosine phosphatase family

Alternative Names

Serine/threonine/tyrosine-interacting protein

Molecular Weight

Mass (kDA):
25.492 kDA

Genomic Context


Human

Location:	14q22.1
Sequence:	14; NC_000014.9 (52730159..52774989)

Subcellular Localizations

Nucleus. Cytoplasm, cytosol. Predominantly localizes to the nucleus.

PTMs

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STYX

References

PMID: 9633825 by Dayton M.A., et al. Multiple phosphotyrosine phosphatase mRNAs are expressed in the human lung fibroblast cell line WI-38.

PMID: 23847209 by Reiterer V., et al. Pseudophosphatase STYX modulates cell-fate decisions and cell migration by spatiotemporal regulation of ERK1/2.