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, No Gclids
Stra8 Antibodies
AND Stra8 ELISA kits, Stra8 Proteins
Many biological assays use antibodies to detect Stra8, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Stra8 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Stra8 antibodies...
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Stra8 Overview
Facts about Stimulated by retinoic acid gene 8 protein.
Stimulated by retinoic acid gene 8 protein (Stra8)
Meiosis-inducer required for the transition to meiosis for both male and female germ cells. In female germ cells, required for premeiotic DNA replication and subsequent events in meiotic prophase.
During spermatogenesis, next to its function in meiotic initiation, promotes (but is not required for) spermatogonial differentiation. Can associate with DNA (maybe in an indirect manner), and in vitro can trigger DNA transcription.
Gene Information
| Mouse | |
|---|---|
| Gene Name: | Stra8 |
| Uniprot: | P70278 |
| Entrez: | 20899 |
Family
| Belongs to: |
|---|
| No superfamily |
Alternative Names
Stimulated by retinoic acid gene 8 protein
Molecular Weight
Mass (kDA):
44.555 kDA
Genomic Context
| Mouse | |
|---|---|
| Location: | 6|6 B1 |
| Sequence: | 6; |
Tissue Specificity
Expressed exclusively in premeiotic germ cells in both sexes. In females, is expressed in the embryonic ovary. In males, is expressed in pubertal and adult testes, in premeiotic spermatogenic cells. Expressed by some type A and B spermatogonia, preleptotene spermatocytes, and early leptotene spermatocytes (at protein level). Expression begins in late undifferntiated spermatogonia and persists during in differentiating spermatogonia (at protein level).
PTMs
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Stra8
bosterbio.com/bosterbio-gene-info-cards/Stra8
References
PMID: 8896602 by Oulad-Abdelghani M., et al. Characterization of a premeiotic germ cell-specific cytoplasmic protein encoded by Stra8, a novel retinoic acid-responsive gene.
PMID: 14550793 by Menke D.B., et al. Sexual differentiation of germ cells in XX mouse gonads occurs in an anterior-to-posterior wave.