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STK39 Antibodies
AND STK39 ELISA kits, STK39 Proteins
Many biological assays use antibodies to detect STK39, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with STK39 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop STK39 antibodies...
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STK39 Infographic by Boster Bio
All STK39 Products
Product
Figures
Specificity
Applications
Price
Human, Mouse, Rat
ELISA
$480
Cat # EKC1550
1 kit, containing one 96-well plate and all necessary reagents
Cat # EKC1550
1 kit, containing one 96-well plate and all necessary reagents
Human, Mouse, Rat
ELISA, Flow Cytometry, IF, ICC, WB
$370
Cat # A02516-3
100 μg/vial
Cat # A02516-3
100 μg/vial
Human, Mouse, Rat
Flow Cytometry, IF, IHC, WB
$523
Cat # M02516
100 µl
Cat # M02516
100 µl
Human, Mouse, Rat
IF, IHC, WB
$523
Cat # M02516-1
100 µl
Cat # M02516-1
100 µl
Human
Flow Cytometry, IHC, WB
$370
Cat # M02516-2
100 μl/vial
Cat # M02516-2
100 μl/vial
STK39 Overview
Facts about STE20/SPS1-related proline-alanine-rich protein kinase.
STE20/SPS1-related proline-alanine-rich protein kinase (STK39)
May act as a mediator of stress-activated signals. Mediates the inhibition of SLC4A4, SLC26A6 in Addition to CFTR actions by the WNK scaffolds, probably through phosphorylation.
Phosphorylates RELT. .
Gene Information
| Human | |
|---|---|
| Gene Name: | STK39 |
| Uniprot: | Q9UEW8 |
| Entrez: | 27347 |
Family
| Belongs to: |
|---|
| protein kinase superfamily |
Alternative Names
DCHTsmall intestine SPAK-like kinase; DKFZp686K05124; EC 2.7.11; EC 2.7.11.1; PASK; proline-alanine-rich STE20-related kinase; serine threonine kinase 39; Serine/threonine-protein kinase 39; SPAKserine threonine kinase 39 (STE20/SPS1 homolog, yeast); STE20/SPS1 homolog; STE20/SPS1-related proline-alanine-rich protein kinase; Ste20-like protein kinase; Ste-20-related kinase
Molecular Weight
Mass (kDA):
59.474 kDA
Genomic Context
| Human | |
|---|---|
| Location: | 2q24.3 |
| Sequence: | 2; NC_000002.12 (167954020..168247595, complement) |
Tissue Specificity
Predominantly expressed in brain and pancreas followed by heart, lung, kidney, skeletal muscle, liver, placenta and testis.
Subcellular Localizations
Cytoplasm. Nucleus. Nucleus when caspase-cleaved.
Diseases
- Hypertensive Disease
- Pseudohypoaldosteronism
- Essential Hypertension
- Malignant Neoplasms
- Neoplasms
- Parkinson Disease
- Arthrogryposis Multiplex Congenita, Distal, Type Iia
- Nervousness
- Pathologic Vasoconstriction
- Physiological Stress
- Inflammation
- Gitelman Syndrome
Interacting Proteins
- CAB39
Pathways
- Transport
- Pathogenesis
- Localization
- Ion Transport
- Excretion
- Secretion
- Cell Differentiation
- Chloride Transport
- Regulation Of Blood Pressure
- Gene Silencing
- Cell Cycle
- Vasoconstriction
- Regulation Of Chloride Transport
PTMs
- Phosphorylation
- Dephosphorylation
- Cleavage
Research Areas
- Protein Kinase
For details, visit:
bosterbio.com/bosterbio-gene-info-cards/STK39
bosterbio.com/bosterbio-gene-info-cards/STK39
References
PMID: 10980603 by Johnston A.M., et al. SPAK, a STE20/SPS1-related kinase that activates the p38 pathway.
PMID: 24722188 by Corominas R., et al. Protein interaction network of alternatively spliced isoforms from brain links genetic risk factors for autism.