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Torsin-1B Antibodies

AND TOR1B ELISA kits, Torsin-1B Proteins

Many biological assays use antibodies to detect Torsin-1B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Torsin-1B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Torsin-1B antibodies...

We validate the specificity of these antibodies to Torsin-1B by testing them on tissues known to express TOR1B positively and negatively. Browse below to find the TOR1B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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TOR1B Infographic by Boster Bio

All TOR1B Products

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Product

Figures

Specificity

Applications

Price

Torsin B (TOR1B) (NM_014506) Human Recombinant Protein

$813
Cat # PROTO14657
20 µg

Torsin B (TOR1B) (NM_014506) Human Over-expression Lysate

Human

$628
Cat # LS027348
100 µg

TOR1B Overview

Facts about Torsin-1B.

TOR1B 3D structure

TOR1B 3D structure. Source: alphafold

Torsin-1B (TOR1B)

May serve as a molecular chaperone assisting in the correct folding of secreted and/or membrane proteins. Plays a role in non-neural cells nuclear envelope and endoplasmic reticulum integrity.

May have a redundant role with TOR1A in non-neural tissues. .

Gene Information

Human
Gene Name:	TOR1B
Uniprot:	O14657
Entrez:	27348

Gene Information

Family

Belongs to:

ClpA/ClpB family

Family

Alternative Names

DQ1MGC4386; Torsin family 1 member B; torsin family 1, member B (torsin B); torsin-1B

Molecular Weight

Mass (kDA):
37.979 kDA

Molecular Weight

Genomic Context


Human

Location:	9q34.11
Sequence:	9; NC_000009.12 (129803143..129811424)

Tissue Specificity

Widely expressed with low levels in brain.

Subcellular Localizations

Endoplasmic reticulum lumen. Nucleus membrane.

Subcellular Localization

Diseases

Dystonia Disorders
Dystonia Musculorum Deformans
Aortic Aneurysm, Abdominal
Dystonia 1, Torsion, Autosomal Dominant
Movement Disorders
Nervousness
Involuntary Movements
Neuroblastoma
Overlying Behavior
Nervous System Disorder
Neuromuscular Diseases
Rem Sleep Behavior Disorder

Parkinson Disease
Dystonia, Primary
Dyskinetic Syndrome
Globus Hystericus
Hallucinations
Pheochromocytoma

Disease

Pathways

Localization
Response To Oxidative Stress
Response To Stress
System Development
Cellular Localization
Neurogenesis
Pathogenesis

Localization Of Cell
Secretion

Pathways

PTMs

Glycosylation

Bosterbio | ELISA Kits, Antibodies, Antibody Company

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/TOR1B

References

PMID: 9288096 by Ozelius L.J., et al. The early-onset torsion dystonia gene (DYT1) encodes an ATP-binding protein.

PMID: 15147511 by Hewett J.W., et al. TorsinB--perinuclear location and association with torsinA.