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- Table of Contents
Facts about CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase.
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Human | |
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Gene Name: | ST3GAL3 |
Uniprot: | Q11203 |
Entrez: | 6487 |
Belongs to: |
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glycosyltransferase 29 family |
alpha 2,3-sialyltransferase III; Alpha 2,3-ST 3; alpha-2,3-sialyltransferase II; Beta-galactoside alpha-2,3-sialyltransferase 3; CMP-N-acetylneuraminate-beta-1,4-galactoside alpha-2,3-sialyltransferase; EC 2.4.99.6; Gal beta-1,3(4) GlcNAc alpha-2,3 sialyltransferase; Gal beta-1,3(4)GlcNAc alpha-2,3 sialyltransferase; MRT12; N-acetyllactosaminide alpha-2,3-sialyltransferase; Sialyltransferase 6; Siat3; SIAT6; SIAT6sialyltransferase 6 (N-acetyllacosaminide alpha 2,3-sialyltransferase); ST3 beta-Gal alpha-2,3-Sialyltransferase 3; ST3 beta-galactoside alpha-2,3-sialyltransferase 3; ST3Gal III; ST3
Mass (kDA):
42.171 kDA
Human | |
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Location: | 1p34.1 |
Sequence: | 1; NC_000001.11 (43707465..43931165) |
Highly expressed in adult skeletal muscle and in all fetal tissues examined and to a much lesser extent in placenta, lung and liver.
Golgi apparatus, Golgi stack membrane; Single-pass type II membrane protein. Secreted. Membrane-bound form in trans cisternae of Golgi. Secreted into the body fluid.
PMID: 8333853 by Kitagawa H., et al. Cloning and expression of human Gal beta 1,3(4)GlcNAc alpha 2,3- sialyltransferase.
PMID: 21907012 by Hu H., et al. ST3GAL3 mutations impair the development of higher cognitive functions.