Hsc70-interacting protein Antibodies

AND ST13 ELISA kits, Hsc70-interacting protein Proteins

Many biological assays use antibodies to detect Hsc70-interacting protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hsc70-interacting protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hsc70-interacting protein antibodies...

We validate the specificity of these antibodies to Hsc70-interacting protein by testing them on tissues known to express ST13 positively and negatively. Browse below to find the ST13 antibody that suites your experiment. We have 5 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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ST13 Infographic by Boster Bio

All ST13 Products

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Product

Figures

Specificity

Applications

Price

Anti-HSC70 Interacting Protein HIP/ST13 Antibody Picoband®

5 Q&As

Human

IF, ICC, WB

$370
Cat # PA1935
100 μg/vial

ST13 (NM_003932) Human Recombinant Protein

$813
Cat # PROTP50502
20 µg

Anti-HSC70 Interacting Protein HIP Rabbit Monoclonal Antibody

Human, Mouse

Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # M05692-1
100 μl/vial

ST13 (NM_003932) Human Over-expression Lysate

Human

$628
Cat # LS006767
100 µg

Anti-ST13 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A05692-1
100 µg/vial

ST13 Overview

Facts about Hsc70-interacting protein.

ST13 3D structure. Source: alphafold

Hsc70-interacting protein (ST13)

One HIP oligomer binds the ATPase domains of at least two HSC70 molecules dependent on activation of the HSC70 ATPase by HSP40. Stabilizes the ADP state of HSC70 which has a high affinity for substrate protein.

Through its own chaperone activity, it may contribute to the interaction of HSC70 with various target proteins (By similarity). .

Gene Information

Human
Gene Name:	ST13
Uniprot:	P50502
Entrez:	6767

Family

Belongs to:

FAM10 family

Alternative Names

AAG2; aging-associated protein 2; FAM10A1FAM10A4; heat shock 70kD protein binding protein; Hip; HIPFLJ27260; HOP; hsc70-interacting protein; Hsp70-interacting protein; HSPABP1; P48MGC129952; PRO0786; Progesterone receptor-associated p48 protein; Protein FAM10A1; Putative tumor suppressor ST13; Renal carcinoma antigen NY-REN-33; SNC6HSPABP; suppression of tumorigenicity 13 (colon carcinoma) (Hsp70 interacting protein); suppression of tumorigenicity 13 (colon carcinoma) (Hsp70-interacting protein); Suppression of tumorigenicity 13 protein

Molecular Weight

Mass (kDA):
41.332 kDA

Genomic Context


Human

Location:	22q13.2
Sequence:	22; NC_000022.11 (40824535..40857008, complement)

Subcellular Localizations

Cytoplasm.

Diseases

Malignant Neoplasms
Neoplasms
Colorectal Cancer
Colorectal Neoplasms
Parkinson Disease
Carcinoma
Cell Invasion
Nerve Degeneration
Pneumonia
Leukemia
Salmonella Infections
Cholangiocarcinoma

Interosseous Desmitis
Finger Injuries
Neoplasm Metastasis
Bile Duct Neoplasms
Metastatic Malignant Neoplasm To The Lymph Node
Melanoma
Malignant Neoplasm Of Breast

Interacting Proteins

APOE
NOS3
PSEN1

Pathways

Localization
Cell Death
Transport
Transposition
Cell Proliferation
Cell Migration
Cell Killing
Electron Transport
Proteolysis
Natriuresis
Virulence
Tropism
Diuresis

Chemotaxis
Fermentation
Reverse Transcription
Protein Folding
Feeding Behavior
Pathogenesis
Excretion

PTMs

Phosphorylation
Cleavage
Nitrosylation

Acetylation
Dephosphorylation
Ubiquitination

Research Areas

Membrane Trafficking and Chaperones

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/ST13

References

PMID: 8721986 by Prapapanich V., et al. Molecular cloning of human p48, a transient component of progesterone receptor complexes and an Hsp70-binding protein.

PMID: 9387309 by Mo Y., et al. Differential expression of HSU17714 gene in colorectal cancer and normal colonic mucosa.