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- Table of Contents
Facts about Protein SSX2.
Human | |
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Gene Name: | SSX2 |
Uniprot: | Q16385 |
Entrez: | 6757 |
Belongs to: |
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SSX family |
Cancer/testis antigen 5.2; cancer/testis antigen family 5, member 2a; CT5.2a; HD21; HOM-MEL-40; MGC119055; MGC15364; MGC3884; protein SSX2; sarcoma, synovial, X-chromosome-related 2; SSX; SSX2A; SSX2B; synovial sarcoma, X breakpoint 2B; synovial sarcoma, X breakpoint 2CT5.2; Tumor antigen HOM-MEL-40
Mass (kDA):
21.62 kDA
Human | |
---|---|
Location: | Xp11.22 |
Sequence: | X; NC_000023.11 (52696896..52707227, complement) |
Expressed at high level in the testis. Expressed at low level in thyroid. Not detected in tonsil, colon, lung, spleen, prostate, kidney, striated and smooth muscles. Detected in rhabdomyosarcoma and fibrosarcoma cell lines. Not detected in mesenchymal and epithelial cell lines.
Nucleus.
PMID: 7539744 by Crew A.J., et al. Fusion of SYT to two genes, SSX1 and SSX2, encoding proteins with homology to the Kruppel-associated box in human synovial sarcoma.
PMID: 7655467 by de Leeuw B., et al. Identification of two alternative fusion genes, SYT-SSX1 and SYT- SSX2, in t(X;18)(p11.2;q11.2)-positive synovial sarcomas.