SSTR4 Antibodies

AND SSTR4 ELISA kits, SSTR4 Proteins

Many biological assays use antibodies to detect SSTR4, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SSTR4 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SSTR4 antibodies...

We validate the specificity of these antibodies to SSTR4 by testing them on tissues known to express SSTR4 positively and negatively. Browse below to find the SSTR4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SSTR4 Infographic by Boster Bio

All SSTR4 Products

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Anti-SSTR4/Somatostatin Receptor 4 Antibody

3 Q&As

Human, Mouse, Rat

ELISA, WB

$335
Cat # A05232
100ul

Anti-Somatostatin Receptor 4 (SSTR4) Mouse Monoclonal Antibody [Clone ID: OTI2F11]

Human, Mouse, Rat

$523
Cat # M05232
100 µl

SSTR4 Overview

Facts about Somatostatin receptor type 4.

SSTR4 3D structure. Source: alphafold

Somatostatin receptor type 4 (SSTR4)

Receptor for somatostatin-14.
The activity of this receptor is mediated by G proteins which inhibits adenylyl cyclase.

It's functionally coupled not only to inhibition of adenylate cyclase, but also to activation of both arachidonate release and mitogen-activated protein (MAP) kinase cascade. Mediates antiproliferative action of somatostatin in tumor cells.

Gene Information

Human
Gene Name:	SSTR4
Uniprot:	P31391
Entrez:	6754

Family

Belongs to:

G-protein coupled receptor 1 family

Alternative Names

G-protein coupled receptor; Somatostatin R4; somatostatin receptor 4; somatostatin receptor type 4; SomatostatinR4; SS4R; SS-4-R; SS4-R; SSTR4

Molecular Weight

Mass (kDA):
42.003 kDA

Genomic Context


Human

Location:	20p11.21
Sequence:	20; NC_000020.11 (23035312..23039237)

Tissue Specificity

Specifically expressed in fetal and adult brain, lung tissue, stomach, and in lesser quantities in the kidney, pituitary and adrenals.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Neoplasms
Pituitary Diseases
Malignant Neoplasms
Adenoma
Carcinoma
Pituitary Neoplasms
Malignant Paraganglionic Neoplasm
Pituitary Adenoma
Nervousness
Neoplasm Metastasis
Prostatic Neoplasms
Malignant Neoplasm Of Prostate
Pertussis

Acromegaly
Adenocarcinoma
Insulinoma
Pancreatic Neoplasm
Neuroendocrine Tumors
Thyroid Neoplasm
Malignant Neoplasm Of Thyroid

Pathways

Secretion
Localization
Cell Proliferation
Hormone Secretion
Insulin Secretion
Cell Migration
Reverse Transcription
Endocytosis
Transport
Glucagon Secretion
Synaptic Transmission
Receptor Internalization
Innervation

Neurogenesis
Cell Cycle Arrest
Cell Cycle
Cell Differentiation
Feeding Behavior
Wound Healing
Exocytosis

PTMs

Phosphorylation

Cleavage

Research Areas

Breast Cancer
Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SSTR4

References

PMID: 8512564 by Xu Y., et al. Molecular cloning and sequencing of a human somatostatin receptor, hSSTR4.

PMID: 8483934 by Rohrer L., et al. Cloning and characterization of a fourth human somatostatin receptor.