SSR1 Antibodies

Translocon-associated protein subunit alpha (SSR1)

TRAP proteins are part of a complex whose function is to bind calcium to the ER membrane and thereby modulate the retention of ER resident proteins. May be involved in the recycling of the translocation apparatus after conclusion of the translocation process or may be the membrane-bound chaperone facilitating folding of translocated proteins.

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Gene Information

Human
Gene Name:	SSR1
Uniprot:	P43307
Entrez:	6745

Family

Belongs to:
TRAP-alpha family

Alternative Names

DKFZp781N23103; FLJ14232; FLJ22100; FLJ23034; FLJ78242; FLJ93042; signal sequence receptor, alpha; SSR alpha subunit; SSR-alpha; translocon-associated protein alpha subunit; translocon-associated protein subunit alpha; TRAP alpha; TRAP-alpha; TRAPASignal sequence receptor subunit alpha

Molecular Weight

Mass (kDA):
32.235 kDA

Genomic Context

Human
Location:	6p24.3
Sequence:	6; NC_000006.12 (7281143..7313199, complement)

Subcellular Localizations

Endoplasmic reticulum membrane; Single-pass type I membrane protein.

Diseases

• Neoplasms
• Neuroblastoma
• Malignant Squamous Cell Neoplasm
• Anxiety Disorders
• Malnutrition
• Double Outlet Right Ventricle
• Allelic Imbalance
• Low Set Ears
• Sudden Infant Death Syndrome
• Hypoxia
• Tissue Adhesions
• Carcinoma

• Mouth Neoplasms
• Malignant Neoplasms
• Paratuberculosis
• Depressive Disorder
• Pertussis
• Neural Crest Tumor

Interacting Proteins

• CANX
• SERPINA1

Pathways

• Cell Cycle
• Habituation
• Cell Growth
• Protein Secretion
• Germination
• Heart Development
• Reflex

• Secretion

PTMs

• Glycoprotein

• Phosphoprotein

Research Areas

• Cell Cycle and Replication

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SSR1

Best Uses Of The SSR1 Marker

The SSR1 gene encodes a small protein called translocon-associated protein subunit alpha (T-AP) that is expressed in cells. This protein can be detected by antibodies against many animals, including rabbits and mice. Boster Bio uses mouse and rabbit to develop its SSR1 antibodies. In addition to regulating the retention of ER resident proteins, T-AP is also involved in recycling the translocation apparatus. It is believed to be part of a chaperone which facilitates the folding translocated proteins.

Boster Bio: Translocon-associated protein subunit alpha

The SSR1 gene encodes an sequence that is specific for the human genome. It has been used in biological assays since years. These antibodies react with SSR1 in a variety of samples from different animals, monoclonal or polyclonal. Boster Bio develops antibodies to the SSR1 gene using mouse and rabbit as model systems. TRAP Proteins, for example are calcium binding proteins found in ER membranes. They can also modulate ER resident proteins retention and may act like membrane-bound chaperones that facilitate folding translocated proteins.

History of Steven Boster

A brief history of Steven Boster may be a useful first step when seeking out this man's past. Boster's achievements and life are marked by many milestones. 1993 was the creation of his first product. Later, he created many products for immunohistochemistry and hundreds of primary antibody. In the late nineties, he became the largest antibody catalog company in China. Boster also invented PicoKine(tm), a proprietary ELISA platform. These ELISA products were created using trade secrets and are a high-quality product.

Steve Boster passed away on June 26, 2022. He was born in Joliet, IL. He was a manager of retail sales for many years. Boster was also a soldier in the U.S. Army. His family includes Crystal Boster and Natosha Peck, his 6 grandchildren, and his 4 brothers Jack Boster & Sandra Blanton. His other siblings are his daughter Lisa Milton, and grandson Cory.

Use the SSR1 marking

The SERPINA1 Vivo DNA in situ hybridization probe by Boster Bio is the best choice to detect the SERPINA1 protein in human tissue. The RNAin situ hybridization probe is composed of purified humanRNA, which binds the gene sequence. After washing the tissue three times with PBS, the tissue sections can be fixed in 4% PFA for 10 min. Then, 100 uL is added to the hybridization solution.

The COMET algorithm identifies single and multi-gene candidate marker panels by incorporating gene-by-cell expression matrices and a 2-dimensional visualization coordinate matrix. The final rank of candidate marker panels is derived as an arithmetic average of these two rankings. For binary and continuous expression data, the top-ranking genes are visualized using visualization coordinates. The COMET algorithm provides statistical and visual outputs that help users understand the data.