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- Table of Contents
Facts about Serine palmitoyltransferase small subunit B.
The SPTLC1-SPTLC2-SPTSSB complex indicates a strong preference for C18-CoA substrate, while the SPTLC1-SPTLC3-SPTSSB isozyme shows an ability to utilize a broader range of acyl-CoAs, without apparent preference (By similarity). .
Mouse | |
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Gene Name: | Sptssb |
Uniprot: | Q925E8 |
Entrez: | 66183 |
Belongs to: |
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SPTSS family |
Serine palmitoyltransferase small subunit B
Mass (kDA):
9.108 kDA
Mouse | |
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Location: | 3|3 E2 |
Sequence: | 3; |
Expression is strong in hypogonadal (hpg) mouse prostate, weak in mature castrated mouse prostate and absent in normal intact or androgen-replaced hpg mouse prostates.
PMID: 15777716 by Singh J., et al. Molecular cloning and characterization of a novel androgen repressible gene expressed in the prostate epithelium.
PMID: 26438849 by Zhao L., et al. Elevation of 20-carbon long chain bases due to a mutation in serine palmitoyltransferase small subunit b results in neurodegeneration.