SPRR2B Antibodies

AND SPRR2B ELISA kits, SPRR2B Proteins

Many biological assays use antibodies to detect SPRR2B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPRR2B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPRR2B antibodies...

We validate the specificity of these antibodies to SPRR2B by testing them on tissues known to express SPRR2B positively and negatively. Browse below to find the SPRR2B antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPRR2B Infographic by Boster Bio

All SPRR2B Products

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SPRR2B (NM_001017418) Human Recombinant Protein

$813
Cat # PROTP35325
20 µg

SPRR2B (NM_001017418) Human Over-expression Lysate

Human

$628
Cat # LS006701
100 µg

SPRR2B Overview

Facts about Small proline-rich protein 2B.

SPRR2B 3D structure. Source: alphafold

Small proline-rich protein 2B (SPRR2B)

Cross-linked envelope protein of keratinocytes. It is a keratinocyte protein that first appears in the cell cytosol, but ultimately becomes cross-linked to membrane proteins by transglutaminase.

All that results in the formation of an insoluble envelope beneath the plasma membrane. .

Gene Information

Human
Gene Name:	SPRR2B
Uniprot:	P35325
Entrez:	6701

Family

Belongs to:

cornifin (SPRR) family

Alternative Names

Small proline-rich protein 2B

Molecular Weight

Mass (kDA):
7.975 kDA

Genomic Context


Human

Location:	1q21.3
Sequence:	1; NC_000001.11 (153070226..153071611, complement)

Tissue Specificity

Suprabasal layers of squamous-differentiated tissues such as epidermis, esophagus, tongue and trachea.

Subcellular Localizations

Cytoplasm.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPRR2B

References

PMID: 8325635 by Gibbs S., et al. Molecular characterization and evolution of the SPRR family of keratinocyte differentiation markers encoding small proline-rich proteins.

PMID: 11279051 by Cabral A., et al. Structural organization and regulation of the small proline-rich family of cornified envelope precursors suggest a role in adaptive barrier function.