Shadow of prion protein Antibodies

AND Sprn ELISA kits, Shadow of prion protein Proteins

Many biological assays use antibodies to detect Shadow of prion protein, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Shadow of prion protein in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Shadow of prion protein antibodies...

We validate the specificity of these antibodies to Shadow of prion protein by testing them on tissues known to express Sprn positively and negatively. Browse below to find the Sprn antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Sprn Infographic by Boster Bio

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SPRN (NM_001012508) Human Over-expression Lysate

Human

$628
Cat # LS503542
100 µg

Sprn Overview

Facts about Shadow of prion protein.

Shadow of prion protein (Sprn)

Prion-like protein which has PrP(C)-such as neuroprotective activity. May act as a modulator for the biological actions of normal and abnormal PrP.

Gene Information

Mouse
Gene Name:	Sprn
Uniprot:	Q8BWU1
Entrez:	212518

Family

Belongs to:

SPRN family

Alternative Names

Shadow of prion protein

Molecular Weight

Mass (kDA):
14.591 kDA

Genomic Context


Mouse

Location:	7\|7 F4
Sequence:	7;

Tissue Specificity

Mainly expressed in brain (at protein level). In brain, it is highly expressed in the hippocampus and cerebellum and is also expressed at lower level in other areas of the brain including the cerebral cortex, the thalamus and the medulla. In hippocampus and cerebellum it is highly expressed in the cell bodies of pyramidal cells and Purkinje cells, respectively.

PTMs

Glycoprotein

GPI-anchor

Lipoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Sprn

References

PMID: 14527721 by Premzl M., et al. Shadoo, a new protein highly conserved from fish to mammals and with similarity to prion protein.

PMID: 17199895 by Premzl M., et al. Comparative genomic analysis of prion genes.