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- Table of Contents
Facts about Sprouty-related, EVH1 domain-containing protein 1.
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Mouse | |
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Gene Name: | Spred1 |
Uniprot: | Q924S8 |
Entrez: | 114715 |
Belongs to: |
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No superfamily |
EVH1/Sprouty domain containing protein; FLJ33903; hSpred1; NFLS; SPRED1; spred-1; sprouty-related, EVH1 domain containing 1; sprouty-related, EVH1 domain-containing protein 1; suppressor of Ras/MAPK activation
Mass (kDA):
50.664 kDA
Mouse | |
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Location: | 2|2 E5 |
Sequence: | 2; |
Expressed in brain. Weakly expressed in lung, heart, liver, kidney, intestine, spleen, testis, thymus, colon and ovary. Also expressed in embryonic tissues such as heart, lung, liver and brain. Highly expressed in IL3-dependent hematopoietic cell lines (Ba/F3 and MC/9) and bone marrow-derived mast cells (BMMC).
PMID: 11493923 by Wakioka T., et al. Spred is a Sprouty-related suppressor of Ras signalling.
PMID: 12646235 by Kato R., et al. Molecular cloning of mammalian Spred-3 which suppresses tyrosine kinase-mediated Erk activation.