This website uses cookies to ensure you get the best experience on our website.
- Table of Contents
Facts about Spindlin-1.
Overexpression induces metaphase arrest and chromosomal instability. Localizes to active rDNA loci and promotes the expression of rRNA genes (PubMed:21960006).
Human | |
---|---|
Gene Name: | SPIN1 |
Uniprot: | Q9Y657 |
Entrez: | 10927 |
Belongs to: |
---|
SPIN/STSY family |
OCR; spindlin 1; spindlin; spindlin-1; SPINOvarian cancer-related protein
Mass (kDA):
29.601 kDA
Human | |
---|---|
Location: | 9q22.1 |
Sequence: | 9; NC_000009.12 (88388444..88478694) |
Highly expressed in ovarian cancer tissues.
Nucleus. Nucleus, nucleolus.
PMID: 16098913 by Gao Y., et al. Spindlin1, a novel nuclear protein with a role in the transformation of NIH3T3 cells.
PMID: 21960006 by Wang W., et al. Nucleolar protein Spindlin1 recognizes H3K4 methylation and stimulates the expression of rRNA genes.