SPIB Antibodies

AND SPIB ELISA kits, SPIB Proteins

Many biological assays use antibodies to detect SPIB, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPIB in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPIB antibodies...

We validate the specificity of these antibodies to SPIB by testing them on tissues known to express SPIB positively and negatively. Browse below to find the SPIB antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPIB Infographic by Boster Bio

All SPIB Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-Spi-B Antibody

1 Q&As

Human

IHC, WB

$341
Cat # A02805
100 µg

Anti-Transcription factor Spi-B SPIB Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A02805-1
0.1 mg

SPIB (NM_003121) Human Over-expression Lysate

Human

$628
Cat # LS006689
100 µg

SPIB Overview

Facts about Transcription factor Spi-B.

SPIB 3D structure. Source: alphafold

Transcription factor Spi-B (SPIB)

Sequence specific transcriptional activator which binds to the PU-box, a purine-rich DNA sequence (5'-GAGGAA-3') that can act as a lymphoid-specific enhancer. Promotes development of plasmacytoid dendritic cells (pDCs), also called type 2 DC precursors (pre-DC2) or natural interferon (IFN)-producing cells.

These cells have the capacity to produce large quantities of interferon and prevent viral replication. May be necessary for B-cell receptor (BCR) signaling, which is vital for normal B-cell development and antigenic stimulation.

Gene Information

Human
Gene Name:	SPIB
Uniprot:	Q01892
Entrez:	6689

Family

Belongs to:

ETS family

Alternative Names

Spi-B transcription factor (Spi-1/PU.1 related); SpiB; Spi-B; transcription factor Spi-B

Molecular Weight

Mass (kDA):
28.819 kDA

Genomic Context


Human

Location:	19q13.33
Sequence:	19; NC_000019.10 (50418938..50431314)

Tissue Specificity

Expressed in plasmacytoid dendritic cells (pDCs) and B-cells, not expressed in T-cells or granulocytes. May also be enriched in stem cell populations of the liver.