Cytospin-B Antibodies

AND SPECC1 ELISA kits, Cytospin-B Proteins

Many biological assays use antibodies to detect Cytospin-B, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Cytospin-B in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Cytospin-B antibodies...

We validate the specificity of these antibodies to Cytospin-B by testing them on tissues known to express SPECC1 positively and negatively. Browse below to find the SPECC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPECC1 Infographic by Boster Bio

All SPECC1 Products

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Specificity

Applications

Price

Human SPECC1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTQ5M775
Starting from 10ug

SPECC1 (NM_001033555) Human Over-expression Lysate

Human

$628
Cat # LS092521
100 µg

SPECC1 Overview

Facts about Cytospin-B.

SPECC1 3D structure. Source: alphafold

Cytospin-B (SPECC1)

Gene Information

Human
Gene Name:	SPECC1
Uniprot:	Q5M775
Entrez:	92521

Family

Belongs to:

cytospin-A family

Alternative Names

cytospin-B; CYTSBcytospin B; FLJ36955; HCMOGT-1; NSP; NSP5; Nuclear structure protein 5; sperm antigen HCMOGT 1; Sperm antigen HCMOGT-1; sperm antigen with calponin homology and coiled coil domains 1; sperm antigen with calponin homology and coiled-coil domains 1cytokinesis and spindle organization B; sperm antigen with calponin-like and coiled coil domains 1; structure protein NSP5a3a; structure protein NSP5a3b; structure protein NSP5b3a; structure protein NSP5b3b

Molecular Weight

Mass (kDA):
118.585 kDA

Genomic Context


Human

Location:	17p11.2
Sequence:	17; NC_000017.11 (20009301..20319026)

Tissue Specificity

Highly expressed in testis. Barely detectable in other tissues. Also highly expressed in some cancer cell lines.

Subcellular Localizations

Nucleus.; [Isoform 3]: Membrane; Lipid-anchor.; [Isoform 4]: Membrane; Lipid-anchor.; [Isoform 5]: Membrane; Lipid-anchor.

Diseases

Malignant Neoplasms
Malignant Squamous Cell Neoplasm
Head And Neck Neoplasms
Head And Neck Carcinoma
Carcinoma
Neck Carcinoma
Cell Transformation, Neoplastic
Juvenile Myelomonocytic Leukemia
Myelomonocytic Leukemia
Neoplasms
Malignant Neck Neoplasm

Leukemia
Chromosomal Translocation
Mammary Neoplasms
Leukemia, Myelomonocytic, Chronic
Myelodysplastic-myeloproliferative Diseases
Malignant Head And Neck Neoplasm

Pathways

Ribosome Biogenesis
Mitosis
Rrna Processing
Cell Division
Cell Growth
Rrna Transcription
Cell Proliferation
Induction Of Apoptosis

Cell Cycle
Cognition

PTMs

Lipoprotein

Myristate

Phosphoprotein

Research Areas

Cancer
Cell Biology
Cell Cycle and Replication
Cellular Markers
Neuroscience

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPECC1

References

PMID: 15602574 by Sang N., et al. A gene highly expressed in tumor cells encodes novel structure proteins.

PMID: 15087372 by Morerio C., et al. HCMOGT-1 is a novel fusion partner to PDGFRB in juvenile myelomonocytic leukemia with t(5;17)(q33;p11.2).