Hyaluronidase PH-20 Antibodies

AND SPAM1 ELISA kits, Hyaluronidase PH-20 Proteins

Many biological assays use antibodies to detect Hyaluronidase PH-20, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Hyaluronidase PH-20 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Hyaluronidase PH-20 antibodies...

We validate the specificity of these antibodies to Hyaluronidase PH-20 by testing them on tissues known to express SPAM1 positively and negatively. Browse below to find the SPAM1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPAM1 Infographic by Boster Bio

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Hyaluronidase PH20 (SPAM1) (NM_003117) Human Over-expression Lysate

Human

$628
Cat # LS006677
100 µg

SPAM1 Overview

Facts about Hyaluronidase PH-20.

SPAM1 3D structure. Source: alphafold

Hyaluronidase PH-20 (SPAM1)

Involved in sperm-egg adhesion. Upon fertilization sperm must first penetrate a layer of cumulus cells that surrounds the egg prior to reaching the zona pellucida.

The cumulus cells are embedded in a matrix containing hyaluronic acid that is formed prior to ovulation. This protein aids in penetrating the layer of cumulus cells by digesting hyaluronic acid.

Gene Information

Human
Gene Name:	SPAM1
Uniprot:	P38567
Entrez:	6677

Family

Belongs to:

glycosyl hydrolase 56 family

Alternative Names

EC 3.2.1.35; HYA1; HYAL1; HYAL3; HYAL5; hyal-PH20; hyaluronidase PH-20; Hyaluronoglucosaminidase PH-20; MGC26532; PH20; PH-20; SPAG15; SPAM1; sperm adhesion molecule 1 (PH-20 hyaluronidase, zona pellucida binding); Sperm adhesion molecule 1; Sperm surface protein PH-20