SPAG6 Antibodies

AND SPAG6 ELISA kits, SPAG6 Proteins

Many biological assays use antibodies to detect SPAG6, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SPAG6 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SPAG6 antibodies...

We validate the specificity of these antibodies to SPAG6 by testing them on tissues known to express SPAG6 positively and negatively. Browse below to find the SPAG6 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SPAG6 Infographic by Boster Bio

All SPAG6 Products

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Product

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Specificity

Applications

Price

SPAG6 (NM_172242) Human Recombinant Protein

$1062
Cat # PROTO75602
20 µg

SPAG6 (NM_172242) Human Over-expression Lysate

Human

$628
Cat # LS009576
100 µg

SPAG6 Overview

Facts about Sperm-associated antigen 6.

SPAG6 3D structure. Source: alphafold

Sperm-associated antigen 6 (SPAG6)

Important for structural integrity of the central apparatus in the sperm tail and for flagellar motility. .

Gene Information

Human
Gene Name:	SPAG6
Uniprot:	O75602
Entrez:	9576

Family

Belongs to:

No superfamily

Alternative Names

axoneme central apparatus protein; DKFZp434I153; pf16; Protein PF16 homolog; Repro-SA-1MGC26276; sperm associated antigen 6; Sperm flagellar protein; sperm-associated antigen 6

Molecular Weight

Mass (kDA):
55.476 kDA

Genomic Context


Human

Location:	10p12.2
Sequence:	10; NC_000010.11 (22345445..22417610)

Subcellular Localizations

Cytoplasm, cytoskeleton. Cell projection, cilium, flagellum. Associated with microtubules. Detected on the sperm flagellum.

Diseases

Infertility
Malignant Neoplasms
Male Infertility
Hydrocephalus
Leukemia, Myelocytic, Acute
Neoplasms
Myeloid Leukemia
Acute Lymphocytic Leukemia
Leukemia
Malignant Neoplasm Of Breast
Lung Diseases
Atelectasis
Neoplasm, Residual

Edema
Tumor Angiogenesis
Dyskinetic Syndrome
Hemorrhage
Nervousness
Mammary Neoplasms
Lymphoma

Pathways

Spermatogenesis
Methylation
Sperm Motility
Cell Differentiation
Pachytene
Gene Silencing
Immune Response
Dna Repair
Dna Methylation
Inner Ear Development
Humoral Immune Response
Demethylation
Ear Development

Prophase
Cell Communication
Angiogenesis
Hair Cell Differentiation
Spinal Cord Development
Rna Interference
Meiosis

PTMs

Methylation

Demethylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SPAG6

References

PMID: 10493827 by Neilson L.I., et al. cDNA cloning and characterization of a human sperm antigen (SPAG6) with homology to the product of the Chlamydomonas PF16 locus.