SP110 Antibodies

AND SP110 ELISA kits, SP110 Proteins

Many biological assays use antibodies to detect SP110, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SP110 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SP110 antibodies...

We validate the specificity of these antibodies to SP110 by testing them on tissues known to express SP110 positively and negatively. Browse below to find the SP110 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SP110 Infographic by Boster Bio

All SP110 Products

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Product

Figures

Specificity

Applications

Price

Anti-IPR1 SP110 Antibody

Human, Mouse, Rat

ELISA, IF, IHC-P, WB

$449
Cat # A03354
0.1 mg

Anti-SP110 Mouse Monoclonal Antibody [Clone ID: OTI4C1]

+17

Human

IHC, WB

$523
Cat # M03354
100 µl

SP110 (NM_004509) Human Over-expression Lysate

Human

$960
Cat # LS003431
100 µg

SP110 Overview

Facts about Sp110 nuclear body protein.

SP110 3D structure. Source: alphafold

Sp110 nuclear body protein (SP110)

Transcription factor. May be a nuclear hormone receptor coactivator.

Enhances transcription of genes with retinoic acid response elements (RARE). .

Gene Information

Human
Gene Name:	SP110
Uniprot:	Q9HB58
Entrez:	3431

Family

Belongs to:

No superfamily

Alternative Names

FLJ22835; IFI41; IFI75; interferon-induced protein 41, 30kD; Interferon-induced protein 41/75; interferon-induced protein 75, 52kD; IPR1; phosphoprotein 41; phosphoprotein 75; SP110 nuclear body protein; Speckled 110 kDa; Transcriptional coactivator Sp110; VODI

Molecular Weight

Mass (kDA):
78.396 kDA

Genomic Context


Human

Location:	2q37.1
Sequence:	2; NC_000002.12 (230165186..230225729, complement)

Tissue Specificity

Highly expressed in peripheral blood leukocytes and spleen. Detected at intermediate levels in thymus, prostate, testis, ovary, small intestine and colon, and at low levels in heart, brain, placenta, lung, liver, skeletal muscle, kidney and pancreas.

Subcellular Localizations

Nucleus. Found in the nuclear body.

Diseases

Tuberculosis
Tuberculosis, Pulmonary
Infective Disorder
Hepatic Veno-occlusive Disease
Venoocclusive Disease
Immunologic Deficiency Syndromes
Acute Promyelocytic Leukemia
Hypogammaglobulinemia
Virus Diseases
Leukemia
Melanoma
Malignant Neoplasms

Neoplasms
Primary Immune Deficiency Disorder
Malaria
Hepatomegaly
Liver Failure
Hiv Infections
Burkitt Lymphoma

Pathways

Cell Death
Pathogenesis
Localization
Methylation
Protein Phosphorylation
Cell Proliferation
Immune Response
Rna Processing

Rna Interference
Chromatin Remodeling

PTMs

Methylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SP110

References

PMID: 7693701 by Kadereit S., et al. Molecular cloning of two new interferon-induced, highly related nuclear phosphoproteins.

PMID: 10913195 by Bloch D.B., et al. Sp110 localizes to the PML-Sp100 nuclear body and may function as a nuclear hormone receptor transcriptional coactivator.