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- Table of Contents
Facts about Gamma-2-syntrophin.
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Human | |
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Gene Name: | SNTG2 |
Uniprot: | Q9NY99 |
Entrez: | 54221 |
Belongs to: |
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syntrophin family |
G2SYNgamma2-syntrophin; gamma-2-syntrophin; MGC133174; SYN5syntrophin 5; syntrophin, gamma 2; syntrophin-5
Mass (kDA):
60.217 kDA
Human | |
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Location: | 2p25.3 |
Sequence: | 2; NC_000002.12 (950849..1367991) |
Widely expressed. Strong expression in brain and testis. In CNS, it is expressed in the perikaryon and proximal portion of the neuronal processes. Strong expression in the hippocampus, neuron-rich dendate granule cells, and pyramidal cell layers. Highly expressed in neurons of the cerebral cortex. Also expressed in the cerebellar cortex, deep cerebellar nuclei, thalamus, and basal ganglia.
Cell membrane, sarcolemma; Peripheral membrane protein; Cytoplasmic side. Cytoplasm, cytoskeleton. In skeletal muscle, it localizes at the cytoplasmic side of the sarcolemmal membrane.
PMID: 10747910 by Piluso G., et al. Gamma1- and gamma2-syntrophins, two novel dystrophin-binding proteins localized in neuronal cells.