SNRPF Antibodies

AND SNRPF ELISA kits, SNRPF Proteins

Many biological assays use antibodies to detect SNRPF, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRPF in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRPF antibodies...

We validate the specificity of these antibodies to SNRPF by testing them on tissues known to express SNRPF positively and negatively. Browse below to find the SNRPF antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNRPF Infographic by Boster Bio

All SNRPF Products

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Specificity

Applications

Price

Anti-SNRPF Antibody

Human, Mouse, Rat

IHC, WB

$405
Cat # A04693
100ul

SNRPF (NM_003095) Human Recombinant Protein

$813
Cat # PROTP62306
20 µg

SNRPF (NM_003095) Human Over-expression Lysate

Human

$628
Cat # LS006636
100 µg

SNRPF Overview

Facts about Small nuclear ribonucleoprotein F.

SNRPF 3D structure. Source: alphafold

Small nuclear ribonucleoprotein F (SNRPF)

Plays role in pre-mRNA splicing as core part of this SMN-Sm complex that mediates spliceosomal snRNP assembly and as part of the spliceosomal U1, U2, U4 and U5 small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome (PubMed:11991638, PubMed:18984161, PubMed:19325628, PubMed:23333303, PubMed:25555158, PubMed:26912367, PubMed:28502770, PubMed:28781166, PubMed:28076346). Part of the pre-catalytic spliceosome B complex and activated spliceosome C complexes (PubMed:11991638, PubMed:28502770, PubMed:28781166, PubMed:28076346).

Is also a part of the minor U12 spliceosome (PubMed:15146077). Included in the U7 snRNP it's involved in histone 3'-end processing (PubMed:12975319).

Gene Information

Human
Gene Name:	SNRPF
Uniprot:	P62306
Entrez:	6636

Family

Belongs to:

snRNP Sm proteins family

Alternative Names

PBSCF; Sm protein F; small nuclear ribonucleoprotein polypeptide F; SMF; Sm-Fsmall nuclear ribonucleoprotein F; snRNP-F

Molecular Weight

Mass (kDA):
9.725 kDA

Genomic Context


Human

Location:	12q23.1
Sequence:	12; NC_000012.12 (95858952..95867053)

Subcellular Localizations

Cytoplasm, cytosol. Nucleus. SMN-mediated assembly into core snRNPs occurs in the cytosol before SMN-mediated transport to the nucleus to be included in spliceosomes.

Diseases

Autoimmunity
Impacted Tooth
Lupus Erythematosus, Systemic
Infertility

Interacting Proteins

CLNS1A
COIL
GEMIN2
GEMIN6
HOMER3

IKZF1
LNX1
LSM5
LSM7
SF3A2

SNRPD2
SNRPE

Pathways

Aging
Oxidative Phosphorylation

PTMs

Phosphorylation

Cleavage

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNRPF

References

PMID: 7744013 by Hermann H., et al. snRNP Sm proteins share two evolutionarily conserved sequence motifs which are involved in Sm protein-protein interactions.

PMID: 11574479 by Pillai R.S., et al. Purified U7 snRNPs lack the Sm proteins D1 and D2 but contain Lsm10, a new 14 kDa Sm D1-like protein.