SNRPC Antibodies

AND SNRPC ELISA kits, SNRPC Proteins

Many biological assays use antibodies to detect SNRPC, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SNRPC in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SNRPC antibodies...

We validate the specificity of these antibodies to SNRPC by testing them on tissues known to express SNRPC positively and negatively. Browse below to find the SNRPC antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SNRPC Infographic by Boster Bio

All SNRPC Products

Product

Figures

Specificity

Applications

Price

SNRPC Human, Small Nuclear Ribonucleoprotein Polypeptide C Human Recombinant Protein, Sf9

Human

$250
Cat # PROTP09234
2ug, 10ug, 1mg

SNRPC (NM_003093) Human Over-expression Lysate

Human

$628
Cat # LS006631
100 µg

Anti-U1-C/SNRPC Antibody Picoband™

+12

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, IHC, ICC, WB

$370
Cat # A07728
100 μg/vial

SNRPC Overview

Facts about U1 small nuclear ribonucleoprotein C.

SNRPC 3D structure. Source: alphafold

U1 small nuclear ribonucleoprotein C (SNRPC)

Component of the spliceosomal U1 snRNP, which is essential for comprehension of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing.

The interaction with the 5' splice-site appears to precede base-pairing involving the pre-mRNA as well as the U1 snRNA. Stimulates devotion or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site area.

Gene Information

Human
Gene Name:	SNRPC
Uniprot:	P09234
Entrez:	6631

Family

Belongs to:

U1 small nuclear ribonucleoprotein C family

Alternative Names

FLJ20302; small nuclear ribonucleoprotein polypeptide C; U1 small nuclear ribonucleoprotein C; U1 small nuclear RNP specific C; U1 snRNP C; U1 snRNP protein C; U1C; U1-C; Yhc1

Molecular Weight

Mass (kDA):
17.394 kDA

Genomic Context


Human

Location:	6p21.31
Sequence:	6; NC_000006.12 (34757094..34773857)

Subcellular Localizations

Nucleus.

Diseases

Lupus Erythematosus, Systemic
Chromosomal Translocation
Autoimmunity
Sclerosis
Mixed Connective Tissue Disease
Malignant Paraganglionic Neoplasm
Autoimmune Diseases
Connective Tissue Diseases
Ewings Sarcoma-primitive Neuroectodermal Tumor (pnet)
Sarcoma
Diffuse Scleroderma

Arthritis
Hypertensive Disease
Autoimmune Reaction
Chondrosarcoma
Extraskeletal Myxoid Chondrosarcoma
Pulmonary Hypertension

Interacting Proteins

RBM10
TIA1
WDR83

Pathways

Localization
Hatching
Oocyte Maturation

PTMs

Acetylation

Phosphoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SNRPC

References

PMID: 2971157 by Sillekens P.T.G., et al. Human U1 snRNP-specific C protein: complete cDNA and protein sequence and identification of a multigene family in mammals.

PMID: 2961811 by Yamamoto K., et al. Isolation and characterization of a complementary DNA expressing human U1 small nuclear ribonucleoprotein C polypeptide.