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- Table of Contents
Facts about Gamma-synuclein.
In vitro, increases the susceptibility of neurofilament-H to calcium-dependent proteases (By similarity). May also function in modulating the keratin network in your skin.
Human | |
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Gene Name: | SNCG |
Uniprot: | O76070 |
Entrez: | 6623 |
Belongs to: |
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synuclein family |
BCSG1; BCSG1PERSYN; Breast cancer-specific gene 1 protein; gamma-Synuclein; persyn; PRSN; SNCG; SRPRSN; Synoretin; synuclein, gamma (breast cancer-specific protein 1); Synuclein-gamma
Mass (kDA):
13.331 kDA
Human | |
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Location: | 10q23.2 |
Sequence: | 10; NC_000010.11 (86955759..86963260) |
Highly expressed in brain, particularly in the substantia nigra. Also expressed in the corpus callosum, heart, skeletal muscle, ovary, testis, colon and spleen. Weak expression in pancreas, kidney and lung.
Cytoplasm, perinuclear region. Cytoplasm, cytoskeleton, microtubule organizing center, centrosome. Cytoplasm, cytoskeleton, spindle. Associated with centrosomes in several interphase cells. In mitotic cells, localized to the poles of the spindle.
PMID: 9044857 by Ji H., et al. Identification of a breast cancer-specific gene, BCSG1, by direct differential cDNA sequencing.
PMID: 9700196 by Ninkina N.N., et al. Organization, expression and polymorphism of the human persyn gene.
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