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- Table of Contents
Facts about Beta-synuclein.
Protects neurons from staurosporine and 6-hydroxy dopamine (6OHDA)-stimulated caspase activation in a p53/TP53- dependent way. Contributes to restore the SNCA anti-apoptotic function abolished by 6OHDA.
Human | |
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Gene Name: | SNCB |
Uniprot: | Q16143 |
Entrez: | 6620 |
Belongs to: |
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synuclein family |
beta-Synuclein; SNCB; synuclein, beta; Synuclein-beta
Mass (kDA):
14.288 kDA
Human | |
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Location: | 5q35.2 |
Sequence: | 5; NC_000005.10 (176620082..176630561, complement) |
Expressed predominantly in brain; concentrated in presynaptic nerve terminals.
Cytoplasm.
PMID: 8194594 by Jakes R., et al. Identification of two distinct synucleins from human brain.
PMID: 9806846 by Lavedan C., et al. Genomic organization and expression of the human beta-synuclein gene (SNCB).