SMNDC1 Antibodies

AND SMNDC1 ELISA kits, SMNDC1 Proteins

Many biological assays use antibodies to detect SMNDC1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMNDC1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMNDC1 antibodies...

We validate the specificity of these antibodies to SMNDC1 by testing them on tissues known to express SMNDC1 positively and negatively. Browse below to find the SMNDC1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SMNDC1 Infographic by Boster Bio

All SMNDC1 Products

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Product

Figures

Specificity

Applications

Price

Human SMNDC1 Recombinant Protein

SDS-PAGE

$250
Cat # PROTO75940
Starting from 10ug

SMNDC1 (NM_005871) Human Over-expression Lysate

Human

$628
Cat # LS010285
100 µg

SMNDC1 Overview

Facts about Survival of motor neuron-related-splicing factor 30.

SMNDC1 3D structure. Source: alphafold

Survival of motor neuron-related-splicing factor 30 (SMNDC1)

Needed for spliceosome assembly. Overexpression causes apoptosis.

Gene Information

Human
Gene Name:	SMNDC1
Uniprot:	O75940
Entrez:	10285

Family

Belongs to:

SMN family

Alternative Names

SMNRSMN-related protein; SPF30splicing factor 30, survival of motor neuron-related; survival motor neuron domain containing 1,30 kDa splicing factor SMNrp; Survival motor neuron domain-containing protein 1; survival of motor neuron-related-splicing factor 30

Molecular Weight

Mass (kDA):
26.711 kDA

Genomic Context


Human

Location:	10q25.2
Sequence:	10; NC_000010.11 (110290730..110304969, complement)

Tissue Specificity

Detected at intermediate levels in skeletal muscle, and at low levels in heart and pancreas.

Subcellular Localizations

Nucleus speckle. Nucleus, Cajal body. Detected in nuclear speckles containing snRNP and in Cajal (coiled) bodies.

Diseases

Muscular Atrophy
Atrophy
Spinal Muscular Atrophy
Hereditary Diseases

Interacting Proteins

KPNB1
PRPF3

Pathways

Methylation
Mrna Splicing
Localization

PTMs

Methylation

Research Areas

Apoptosis

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SMNDC1

References

PMID: 9731529 by Neubauer G., et al. Mass spectrometry and EST-database searching allows characterization of the multi-protein spliceosome complex.

PMID: 9817934 by Talbot K., et al. Characterization of a gene encoding survival motor neuron (SMN)- related protein, a constituent of the spliceosome complex.