Smdt1 Antibodies

AND Smdt1 ELISA kits, Smdt1 Proteins

Many biological assays use antibodies to detect Smdt1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smdt1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smdt1 antibodies...

We validate the specificity of these antibodies to Smdt1 by testing them on tissues known to express Smdt1 positively and negatively. Browse below to find the Smdt1 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Smdt1 Infographic by Boster Bio

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C22orf32 (SMDT1) (NM_033318) Human Over-expression Lysate

Human

$628
Cat # LS091689
100 µg

Smdt1 Overview

Facts about Essential MCU regulator, mitochondrial.

Essential MCU regulator, mitochondrial (Smdt1)

Essential regulatory subunit of the mitochondrial calcium uniporter complicated (uniplex), a complex that mediates calcium uptake into mitochondria (PubMed:27001609). Required to bridge the calcium-sensing proteins MICU1 and MICU2 with the calcium-conducting subunit MCU.

Plays a central role in regulating the uniplex complicated response to intracellular calcium signaling. Acts by mediating activation of MCU and retention of MICU1 to the MCU pore, in order to guarantee tight regulation of this uniplex complicated and proper responses to intracellular calcium signaling (By similarity).

Gene Information

Mouse
Gene Name:	Smdt1
Uniprot:	Q9DB10
Entrez:	69029

Family

Belongs to:

SMDT1/EMRE family

Alternative Names

Essential MCU regulator, mitochondrial

Molecular Weight

Mass (kDA):
11.542 kDA

Genomic Context


Mouse

Location:	15\|15 E1
Sequence:	15;

Tissue Specificity

Widely expressed.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Smdt1

References

PMID: 24231807 by Sancak Y., et al. EMRE is an essential component of the mitochondrial calcium uniporter complex.

PMID: 27001609 by Yamamoto T., et al. Analysis of the structure and function of EMRE in a yeast expression system.