SMC2 Antibodies

AND SMC2 ELISA kits, SMC2 Proteins

Many biological assays use antibodies to detect SMC2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SMC2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SMC2 antibodies...

We validate the specificity of these antibodies to SMC2 by testing them on tissues known to express SMC2 positively and negatively. Browse below to find the SMC2 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SMC2 Infographic by Boster Bio

All SMC2 Products

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Anti-SMC2 Antibody Picoband®

Human, Mouse, Rat

ELISA, Flow Cytometry, IF, ICC, WB

$370
Cat # A04804-2
100 μg/vial

SMC2 Overview

Facts about Structural maintenance of chromosomes protein 2.

SMC2 3D structure. Source: alphafold

Structural maintenance of chromosomes protein 2 (SMC2)

Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases.

Gene Information

Human
Gene Name:	SMC2
Uniprot:	O95347
Entrez:	10592

Family

Belongs to:

SMC family

Alternative Names

CAP-E; CAPESMC2 structural maintenance of chromosomes 2-like 1 (yeast); Chromosome-associated protein E; FLJ10093; hCAP-EXCAP-E homolog; SMC protein 2; SMC2 (structural maintenance of chromosomes 2, yeast)-like 1; SMC2 structural maintenance of chromosomes 2-like 1; SMC-2; SMC2L1; structural maintenance of chromosomes (SMC) family member; structural maintenance of chromosomes 2; structural maintenance of chromosomes protein 2

Molecular Weight

Mass (kDA):
135.656 kDA

Genomic Context


Human

Location:	9q31.1
Sequence:	9; NC_000009.12 (104093760..104141419)

Subcellular Localizations

Nucleus. Cytoplasm. Chromosome. In interphase cells, the majority of the condensin complex is found in the cytoplasm, while a minority of the complex is associated with chromatin. A subpopulation of the complex however remains associated with chromosome foci in interphase cells. During mitosis, most of the condensin complex is associated with the chromatin. At the onset of prophase, the regulatory subunits of the complex are phosphorylated by CDC2, leading to condensin's association with chromosome arms and to chromosome condensation. Dissociation from chromosomes is observed in late telophase