Smarcad1 Antibodies

AND Smarcad1 ELISA kits, Smarcad1 Proteins

Many biological assays use antibodies to detect Smarcad1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Smarcad1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Smarcad1 antibodies...

We validate the specificity of these antibodies to Smarcad1 by testing them on tissues known to express Smarcad1 positively and negatively. Browse below to find the Smarcad1 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Smarcad1 Infographic by Boster Bio

All Smarcad1 Products

Filter by Application:

Product

Figures

Specificity

Applications

Price

Anti-SMARCAD1 Antibody Picoband®

6 Q&As

Human, Mouse, Rat

ELISA, Flow Cytometry, IP, IF, IHC, ICC, WB

$370
Cat # A06049-1
100 μg/vial

Anti-SMARCAD1 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A06049
100ul

SMARCAD1 (NM_020159) Human Recombinant Protein

$813
Cat # PROTQ9H4L7
20 µg

SMARCAD1 (NM_020159) Human Over-expression Lysate

Human

$628
Cat # LS056916
100 µg

Smarcad1 Overview

Facts about SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1.

SWI/SNF-related matrix-associated actin-dependent regulator of chromatin subfamily A containing DEAD/H box 1 (Smarcad1)

DNA helicase that possesses intrinsic ATP-dependent nucleosome-remodeling action and is both required for DNA repair and heterochromatin organization. Encourages DNA end resection of double-strand breaks (DSBs) following DNA damage: probably acts by weakening histone DNA interactions in nucleosomes flanking DSBs.

Required for the restoration of heterochromatin organization after replication. Acts at replication sites to ease the maintenance of heterochromatin by directing H3 and H4 histones deacetylation, H3'Lys-9' trimethylation (H3K9me3) and restoration of silencing (By similarity).

Gene Information

Mouse
Gene Name:	Smarcad1
Uniprot:	Q04692
Entrez:	13990

Family

Belongs to:

SNF2/RAD54 helicase family

Alternative Names

ATP-dependent helicase 1; DKFZP762K2015; EC 3.6.1; EC 3.6.4.12; HEL1; hHEL1; KIAA1122ETL1DKFZp762K2015; subfamily a, containing DEAD/H box 1; SWI/SNF-related matrix-associated actin-dependent regulator of chromatinsubfamily A containing DEAD/H box 1; SWI/SNF-related, matrix-associated actin-dependent regulator of chromatin

Molecular Weight

Mass (kDA):
116.451 kDA

Genomic Context


Mouse

Location:	6 C1\|6 30.11 cM
Sequence:	6;

Diseases

Malignant Neoplasms
Carcinoma
Liver Carcinoma
Carcinogenesis
Neoplasms
Nervousness
Malignant Squamous Cell Neoplasm
Hematologic Neoplasms
Leiomyosarcoma
Hepatitis
Genomic Instability
Head And Neck Carcinoma
Hepatitis B

Hepatocarcinogenesis
Congenital Foot Deformity
Neoplasms, Germ Cell And Embryonal
Malignant Neoplasm Of Stomach
Head And Neck Neoplasms
Liver Neoplasms
Congenital Hand Deformities

Pathways

Chromatin Remodeling
Localization
Dna Replication
Histone Deacetylation
Atp-dependent Chromatin Remodeling
Cell Proliferation
Dna Repair
Neurogenesis
Chromosome Segregation
Rna Splicing
Methylation

Regeneration
Mrna Splicing
Cell Cycle
Chromatin Organization
Pathogenesis

PTMs

Deacetylation

Cleavage

Methylation

Research Areas

DNA Repair

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Smarcad1

References

PMID: 1489724 by Soininen R., et al. The mouse Enhancer trap locus 1 (Etl-1): a novel mammalian gene related to Drosophila and yeast transcriptional regulator genes.

PMID: 8219362 by Schoor M., et al. The Etl-1 gene encodes a nuclear protein differentially expressed during early mouse development.