Slx1b Antibodies

AND Slx1b ELISA kits, Slx1b Proteins

Many biological assays use antibodies to detect Slx1b, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Slx1b in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Slx1b antibodies...

We validate the specificity of these antibodies to Slx1b by testing them on tissues known to express Slx1b positively and negatively. Browse below to find the Slx1b antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slx1b Infographic by Boster Bio

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GIYD2 (SLX1B) (NM_178044) Human Over-expression Lysate

Human

$628
Cat # LS079008
100 µg

Slx1b Overview

Facts about Structure-specific endonuclease subunit SLX1.

Slx1b 3D structure. Source: alphafold

Structure-specific endonuclease subunit SLX1 (Slx1b)

Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.

Has a taste for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.

Gene Information

Mouse
Gene Name:	Slx1b
Uniprot:	Q8BX32
Entrez:	75764

Family

Belongs to:

SLX1 family

Alternative Names

EC 3.6.1.-; FLJ23439; GIYD1; GIYD2; GIY-YIG domain containing 2; GIY-YIG domain-containing protein 1; MGC2532; MGC5178; SLX1 structure-specific endonuclease subunit homolog B (S. cerevisiae); SLX1; SLX1A; structure-specific endonuclease subunit SLX1

Molecular Weight

Mass (kDA):
30.656 kDA

Genomic Context


Mouse

Location:	7\|7 F3
Sequence:	7;

Tissue Specificity

Expressed in testis, colon, bone marrow, brain, thymus and to a lesser extent in heart, kidney, skeletal muscle and spleen.

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slx1b

References

PMID: 27010503 by Braun J., et al. The GIY-YIG type endonuclease ankyrin repeat and LEM domain- containing protein 1 (ANKLE1) is dispensable for mouse hematopoiesis.