SLX1A Antibodies

AND SLX1A ELISA kits, SLX1A Proteins

Many biological assays use antibodies to detect SLX1A, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLX1A in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLX1A antibodies...

We validate the specificity of these antibodies to SLX1A by testing them on tissues known to express SLX1A positively and negatively. Browse below to find the SLX1A antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLX1A Infographic by Boster Bio

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SLX1 (SLX1A) (NM_001015000) Human Over-expression Lysate

Human

$628
Cat # LS548593
100 µg

SLX1A Overview

Facts about Structure-specific endonuclease subunit SLX1.

SLX1A 3D structure. Source: alphafold

Structure-specific endonuclease subunit SLX1 (SLX1A)

Catalytic subunit of the SLX1-SLX4 structure-specific endonuclease that resolves DNA secondary structures generated during DNA repair and recombination. Has endonuclease activity towards branched DNA substrates, introducing single-strand cuts in duplex DNA close to junctions with ss-DNA.

Has a preference for 5'-flap structures, and promotes symmetrical cleavage of static and migrating Holliday junctions (HJs). Resolves HJs by generating two pairs of ligatable, nicked duplex products.

Gene Information

Human
Gene Name:	SLX1A
Uniprot:	Q9BQ83
Entrez:	548593

Family

Belongs to:

SLX1 family

Alternative Names

Structure-specific endonuclease subunit SLX1

Molecular Weight

Mass (kDA):
30.771 kDA

Genomic Context


Human

Location:	16p11.2
Sequence:	16; NC_000016.10 (30193843..30197566)

Subcellular Localizations

Nucleus.

Interacting Proteins

SLX4

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLX1A

References

PMID: 15358107 by Hildebrandt M.A.T., et al. Human SULT1A3 pharmacogenetics: gene duplication and functional genomic studies.

PMID: 19596235 by Svendsen J.M., et al. Mammalian BTBD12/SLX4 assembles a Holliday junction resolvase and is required for DNA repair.