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- Table of Contents
Facts about Sodium/hydrogen exchanger 1.
Plays an essential role in signal transduction. .
Human | |
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Gene Name: | SLC9A1 |
Uniprot: | P19634 |
Entrez: | 6548 |
Belongs to: |
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monovalent cation:proton antiporter 1 (CPA1) transporter (TC 2.A.36) family |
APNH; APNH1; APNHFLJ42224; Na(+)/H(+) antiporter, amiloride-sensitive; Na(+)/H(+) exchanger 1; Na+/H+, amiloride sensitive); Na-Li countertransporter; NHE1; NHE-1; NHE1Na+/H+ antiporter, amiloride-sensitive; SLC9A1; sodium/hydrogen exchanger 1; solute carrier family 9 (sodium/hydrogen exchanger), isoform 1 (antiporter; solute carrier family 9 (sodium/hydrogen exchanger), member 1 (antiporter; solute carrier family 9 (sodium/hydrogen exchanger), member 1; Solute carrier family 9 member 1
Mass (kDA):
90.763 kDA
Human | |
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Location: | 1p36.11 |
Sequence: | 1; NC_000001.11 (27098809..27155125, complement) |
Kidney and intestine.
Membrane; Multi-pass membrane protein. Endoplasmic reticulum membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Colocalizes with CHP1 at the reticulum endoplasmic (By similarity). Colocalizes with CHP1 and CHP2 at the plasma membrane.
PMID: 2536298 by Sardet C., et al. Molecular cloning, primary structure, and expression of the human growth factor-activatable Na+/H+ antiporter.
PMID: 2154036 by Sardet C., et al. Growth factors induce phosphorylation of the Na+/H+ antiporter, glycoprotein of 110 kD.