SLC7A5 Antibodies

AND SLC7A5 ELISA kits, SLC7A5 Proteins

Many biological assays use antibodies to detect SLC7A5, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC7A5 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC7A5 antibodies...

We validate the specificity of these antibodies to SLC7A5 by testing them on tissues known to express SLC7A5 positively and negatively. Browse below to find the SLC7A5 antibody that suites your experiment. We have 4 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC7A5 Infographic by Boster Bio

All SLC7A5 Products

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Product

Figures

Specificity

Applications

Price

Anti-Hu CD98 Purified SLC7A5 Monoclonal Antibody

Human

Flow Cytometry, IP, IHC-P

$301
Cat # M01016
0.1 mg

Anti-SLC7A5 Antibody

Human, Mouse, Rat

IF, ICC, WB

$405
Cat # A01016
100ul

Anti-SLC7A5 Antibody (N-Term)

Human

IF, WB

$299
Cat # M01016-1
50 µl

SLC7A5 (NM_003486) Human Over-expression Lysate

Human

$628
Cat # LS008140
100 µg

SLC7A5 Overview

Facts about Large neutral amino acids transporter small subunit 1.

SLC7A5 3D structure. Source: alphafold

Large neutral amino acids transporter small subunit 1 (SLC7A5)

Sodium-independent, high-affinity transport of large neutral amino acids such as phenylalanine, tyrosine, leucine, arginine and tryptophan, when connected with SLC3A2/4F2hc. Involved in cellular amino acid uptake.

Acts as an amino acid exchanger. Involved in the transport of L-DOPA throughout the blood- brain barrier, and that of thyroid hormones triiodothyronine (T3) and thyroxine (T4) across the cell membrane in cells like placenta.

Gene Information

Human
Gene Name:	SLC7A5
Uniprot:	Q01650
Entrez:	8140

Family

Belongs to:

amino acid-polyamine-organocation (APC) superfamily

Alternative Names

4F2 LC; 4F2LC; CD98; CD98lc; D16S469EL-type amino acid transporter 1; E16; Integral membrane protein E16; large neutral amino acids transporter 1; large neutral amino acids transporter small subunit 1; LAT1; LAT1hLAT1; MPE16; MPE16CD98 light chain; SLC7A5; sodium-independent neutral amino acid transporter LAT1,4F2LC; solute carrier family 7 (cationic amino acid transporter, y+ system), member 5,4F2 light chain; Solute carrier family 7 member 5; TA1; y+ system cationic amino acid transporter

Molecular Weight

Mass (kDA):
55.01 kDA

Genomic Context


Human

Location:	16q24.2
Sequence:	16; NC_000016.10 (87830022..87869507, complement)

Tissue Specificity

Expressed abundantly in adult lung, liver, brain, skeletal muscle, placenta, bone marrow, testis, resting lymphocytes and monocytes, and in fetal liver. Weaker expression in thymus, cornea, retina, peripheral leukocytes, spleen, kidney, colon and lymph node. During gestation, expression in the placenta was significantly stronger at full-term than at the mid-trimester stage. Also expressed in all human tumor cell lines tested and in the astrocytic process of primary astrocytic gliomas. Expressed in retinal endothelial cells and in the intestinal epithelial cell line Caco-2.

Subcellular Localizations

Apical cell membrane; Multi-pass membrane protein. Cell membrane; Multi-pass membrane protein. Lysosome membrane; Multi-pass membrane protein. Located to the plasma membrane by SLC3A2/4F2hc (PubMed:9751058). Localized to the apical membrane of placental syncytiotrophoblastic cells (PubMed:11742812). Recruited to lysosomes by LAPTM4B (PubMed:25998567). Expressed in both luminal and abluminal membranes of brain capillary endothelial cells (By similarity).