SLC4A10 Antibodies

AND SLC4A10 ELISA kits, SLC4A10 Proteins

Many biological assays use antibodies to detect SLC4A10, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC4A10 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC4A10 antibodies...

We validate the specificity of these antibodies to SLC4A10 by testing them on tissues known to express SLC4A10 positively and negatively. Browse below to find the SLC4A10 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC4A10 Infographic by Boster Bio

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SLC4A10 Overview

Facts about Sodium-driven chloride bicarbonate exchanger.

SLC4A10 3D structure. Source: alphafold

Sodium-driven chloride bicarbonate exchanger (SLC4A10)

Electrogenic sodium/bicarbonate cotransporter in exchange for intracellular chloride. Plays an important role in regulating intracellular pH (By similarity).

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Gene Information

Human
Gene Name:	SLC4A10
Uniprot:	Q6U841
Entrez:	57282

Family

Belongs to:

anion exchanger (TC 2.A.31) family

Alternative Names

sodium bicarbonate cotransporter-like, member 10; sodium bicarbonate transporter-like, member 10; sodium-driven chloride bicarbonate exchanger; Solute carrier family 4 member 10; solute carrier family 4, sodium bicarbonate transporter, member 10

Molecular Weight

Mass (kDA):
125.946 kDA

Genomic Context


Human

Location:	2q24.2
Sequence:	2; NC_000002.12 (161620963..161985276)

Subcellular Localizations

Basolateral cell membrane; Multi-pass membrane protein. Apical cell membrane; Multi-pass membrane protein. Cell projection, dendrite. Cell projection, axon. Perikaryon. Cell junction, synapse, presynapse. Cell junction, synapse, postsynapse. Detected in dendrites and axon terminals of retinal OFF bipolar cells and in axon terminals of ON bipolar cells. In amacrine cells, located in the perikaryon. Also detected in basal and apical dendrites of hippocampal pyramidal cells.

Diseases

Disease Of Adrenal Medulla
Epilepsy
Nervousness
Hydrocephalus, Normal Pressure
Glaucoma, Open-angle
Hypoxia
Epilepsy, Complex Partial
Hydrocephalus
Epilepsy, Frontal Lobe
Chromosome Breakage
Peripheral Circulatory Failure
Cytogenetic Abnormality

Anoxia
Primary Open Angle Glaucoma
Acidosis
Intraocular Pressure Disorder
Intracranial Hypertension
Glaucoma

Pathways

Transport
Secretion
Pathogenesis
Localization
Bicarbonate Transport
Anion Transport
Signal Transmission
Aging

Ion Transport
Glycosylation
Cognition

PTMs

Phosphorylation

Glycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC4A10

References

PMID: 10993873 by Wang C.-Z., et al. The Na+-driven Cl-/HCO3- exchanger. Cloning, tissue distribution, and functional characterization.

PMID: 18319254 by Parker M.D., et al. Characterization of human SLC4A10 as an electroneutral Na/HCO3 cotransporter (NBCn2) with Cl- self-exchange activity.