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- Table of Contents
Facts about Zinc transporter ZIP4.
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Human | |
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Gene Name: | SLC39A4 |
Uniprot: | Q6P5W5 |
Entrez: | 55630 |
Belongs to: |
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ZIP transporter (TC 2.A.5) family |
acrodermatitis enteropathica, zinc-deficiency type; AEZ; FLJ20327; MGC74741; SLC39A4; solute carrier family 39 (zinc transporter), member 4; Solute carrier family 39 member 4; zinc transporter ZIP4; ZIP4; ZIP-4; ZIP4AEZ; Zrt- and Irt-like protein 4
Mass (kDA):
68.408 kDA
Human | |
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Location: | 8q24.3 |
Sequence: | 8; NC_000008.11 (144412414..144417146, complement) |
Highly expressed in kidney, small intestine, stomach, colon, jejunum and duodenum.
Cell membrane; Multi-pass membrane protein. Recycling endosome membrane; Multi-pass membrane protein. Colocalized with TFRC in the recycling endosomes. Cycles between endosomal compartments and the plasma membrane in response to zinc availability.
PMID: 12068297 by Kuery S., et al. Identification of SLC39A4, a gene involved in acrodermatitis enteropathica.
PMID: 12032886 by Wang K., et al. A novel member of a zinc transporter family is defective in acrodermatitis enteropathica.