SLC38A3 Antibodies

AND SLC38A3 ELISA kits, SLC38A3 Proteins

Many biological assays use antibodies to detect SLC38A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC38A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC38A3 antibodies...

We validate the specificity of these antibodies to SLC38A3 by testing them on tissues known to express SLC38A3 positively and negatively. Browse below to find the SLC38A3 antibody that suites your experiment. We have 1 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC38A3 Infographic by Boster Bio

All SLC38A3 Products

Product

Figures

Specificity

Applications

Price

SLC38A3 (NM_006841) Human Over-expression Lysate

Human

$628
Cat # LS010991
100 µg

SLC38A3 Overview

Facts about Sodium-coupled neutral amino acid transporter 3.

SLC38A3 3D structure. Source: alphafold

Sodium-coupled neutral amino acid transporter 3 (SLC38A3)

Sodium-dependent amino acid/proton antiporter. Mediates electrogenic cotransport of glutamine and sodium ions in exchange for protons.

Also recognizes histidine, asparagine and alanine. May mediate amino acid transfer in either direction under physiological conditions.

Gene Information

Human
Gene Name:	SLC38A3
Uniprot:	Q99624
Entrez:	10991

Family

Belongs to:

amino acid/polyamine transporter 2 family

Alternative Names

G17sodium-coupled neutral amino acid transporter 3; Na(+)-coupled neutral amino acid transporter 3; NAT1; N-system amino acid transporter 1; SN1system N1 Na+ and H+-coupled glutamine transporter; SNAT3; Solute carrier family 38 member 3; solute carrier family 38, member 3; System N amino acid transporter 1

Molecular Weight

Mass (kDA):
55.773 kDA

Genomic Context


Human

Location:	3p21.31
Sequence:	3; NC_000003.12 (50205268..50221486)

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Neuroblastoma
Metabolic Acidosis
Acidosis
Reperfusion Injury
Endometrial Polyp
Pre-eclampsia
Carcinoma
Immunologic Deficiency Syndromes
Fibrosarcoma
Neoplasms
Severe Combined Immunodeficiency
Nervousness

Renal Cell Carcinoma
Zinc Deficiency Disorder
Vaccinia
Neurotoxicity Syndromes
Renal Tubular Acidosis
Hypertensive Disease
Potassium Deficiency

Pathways

Transport
Localization
Antiport
Glutamine Transport
Amino Acid Transport
Excretion
Secretion
L-alanine Transport
Pigmentation
Hypersensitivity
Myelination
Bicarbonate Transport
Autocrine Signaling

Cell Differentiation
Cumulus Cell Differentiation
Meiosis
Oligodendrocyte Development
Oligodendrocyte Differentiation
Sensory Processing
Extracellular Transport

PTMs

Phosphorylation

Reduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC38A3

References

PMID: 10823827 by Fei Y.-J., et al. Primary structure, genomic organization, and functional and electrogenic characteristics of human system N 1, a Na+- and H+- coupled glutamine transporter.

PMID: 11085536 by Lerman M.I., et al. The 630-kb lung cancer homozygous deletion region on human chromosome 3p21.3: identification and evaluation of the resident candidate tumor suppressor genes.