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- Table of Contents
Facts about Solute carrier family 2, facilitated glucose transporter member 12.
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Human | |
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Gene Name: | SLC2A12 |
Uniprot: | Q8TD20 |
Entrez: | 154091 |
Belongs to: |
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major facilitator superfamily |
GLUT-12; GLUT12GLUT8Glucose transporter type 12; solute carrier family 2 (facilitated glucose transporter), member 12; solute carrier family 2, facilitated glucose transporter member 12
Mass (kDA):
66.966 kDA
Human | |
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Location: | 6q23.2 |
Sequence: | 6; NC_000006.12 (133987581..134052651, complement) |
Predominantly expressed in skeletal muscle, heart and prostate, with lower levels in brain, placenta and kidney.
Cell membrane; Multi-pass membrane protein. Endomembrane system; Multi-pass membrane protein. Cytoplasm, perinuclear region. Localizes primarily perinuclear region in the absence of insulin.
In this article, we will discuss Boster Bio's Anti-GLUT12/SLC2A12 Marker. We will also be discussing the company's high affinity primary antibodies and how they were validated on IHC/WB. Boster's gene informationgraphics will be shared, which will help you to make the most of this marker. Here are the key facts regarding Boster's AntiGLUT12/SLC2A12 marker.
Boster Bio Anti-GLUT12/ssc2a12 Marker is a high-affinity antibody tested in Western Blotting and Immunohistochemistry. This antibody recognizes the mouse GLUT12 C-terminus. This antibody can be used in a variety applications. The product's approved peptide is derived using rabbit serum.
Flow cytometry can be used to analyze proteins in biological samples. It involves the analysis these proteins or particles in the presence of or without a color. Boster Bio provides high-affinity monoclonal and multiclonal primary antibodies against this marker. These antibodies have been in existence for more 25 years and are highly cited.
Primary antibodies are produced by immunizing a host animal with a specific antigen. These antibodies are highly dependent on their specificity and affinity, which are determined by the characteristics of the antigen. High specificity means that the antibodies do not bind to unintended antigens. Good primary antibodies will recognize, purify and measure antigens of interest.
Secondary antibodies can be made using the same primary antibodies but have different binding affinities. These antibodies are typically used as core elements in experiments and assays. The primary antibodies bind antigens and can be used in a wide variety of methods, including Western Blotting, immunohistochemistry, histopathology, and ELISA. Flowcytometry, on other hand, measures the number specific cell types.
Primary antibodies should be validated on multiple platforms in order to achieve the best results. Boster Bio has over 16,000 antibodies. These include WB and IHC-validated antibody. Boster also offers eBooks to help you get started in immunohistochemistry. These eBooks cover the basics in WB, IHC Flow, and CHIP. You can also download a sample ELISA that you can use with the antibodies.
The primary antibody bound the target protein to the antigen is called the antigen. Boster Bio makes secondary antibodies for Western Blotting and IHC. Secondary antibodies are made from a polyclonal antigen. They are usually very specific for the antigen. Secondary antibodies are not recommended to be used as a separate product. They can bind at multiple targets. The antibodies from Boster Bio are a great option for testing different proteins in a single experiment.
PMID: 11832379 by Rogers S., et al. Identification of a novel glucose transporter-like protein -- GLUT- 12.