SLC28A3 Antibodies

AND SLC28A3 ELISA kits, SLC28A3 Proteins

Many biological assays use antibodies to detect SLC28A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC28A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC28A3 antibodies...

We validate the specificity of these antibodies to SLC28A3 by testing them on tissues known to express SLC28A3 positively and negatively. Browse below to find the SLC28A3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC28A3 Infographic by Boster Bio

All SLC28A3 Products

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Specificity

Applications

Price

Anti-SLC28A3 Antibody

Human, Mouse

$405
Cat # A05336
100ul

SLC28A3 (NM_022127) Human Over-expression Lysate

Human

$628
Cat # LS064078
100 µg

SLC28A3 Overview

Facts about Solute carrier family 28 member 3.

SLC28A3 3D structure. Source: alphafold

Solute carrier family 28 member 3 (SLC28A3)

Sodium-dependent, pyrimidine- and purine-selective. Involved in the homeostasis of endogenous nucleosides.

Exhibits the transport characteristics of the nucleoside transport system cib or N3 subtype (N3/cib) (with marked transportation of both thymidine and inosine). Employs a 2:1 sodium/nucleoside ratio.

Gene Information

Human
Gene Name:	SLC28A3
Uniprot:	Q9HAS3
Entrez:	64078

Family

Belongs to:

concentrative nucleoside transporter (CNT) (TC 2.A.41) family

Alternative Names

CNT 3; CNT3concentrative Na+-nucleoside cotransporter; Concentrative Na(+)-nucleoside cotransporter 3; hCNT3; solute carrier family 28 (sodium-coupled nucleoside transporter), member 3; solute carrier family 28 member 3

Molecular Weight

Mass (kDA):
76.93 kDA

Genomic Context


Human

Location:	9q21.32-q21.33
Sequence:	9; NC_000009.12 (84273123..84368727, complement)

Tissue Specificity

Expressed in pancreas, bone marrow, trachea, mammary gland, liver, prostate, and regions of intestine, brain, lung, placenta, testis, kidney, and heart.

Subcellular Localizations

[Isoform 1]: Cell membrane; Multi-pass membrane protein.; [Isoform 2]: Endoplasmic reticulum membrane; Multi-pass membrane protein.

Diseases

Neoplasms
Hepatitis
Hepatitis C
Hepatitis, Chronic
Hepatitis C, Chronic
Congenital Dyserythropoietic Anemia
Malignant Neoplasms
Diabetic Nephropathy
Malignant Neoplasm Of Lung
Leukemia, Myelocytic, Acute
Malignant Childhood Neoplasm
Hemolysis (disorder)

Myeloid Leukemia
Hyperglycemia
Cytogenetic Abnormality
Loss Of Chromosome 9q
Hiv-associated Lipodystrophy Syndrome
Infective Disorder
Lipodystrophy

Pathways

Transport
Nucleoside Salvage
Localization
Transmembrane Transport
Cell Cycle
Nucleoside Transport
Intracellular Nucleoside Transport

Uridine Transport
Secretion

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC28A3

References

PMID: 11032837 by Ritzel M.W.L., et al. Molecular identification and characterization of novel human and mouse concentrative Na+-nucleoside cotransporter proteins (hCNT3 and mCNT3) broadly selective for purine and pyrimidine nucleosides (system cib).

PMID: 15861042 by Damaraju S., et al. Identification and functional characterization of variants in human concentrative nucleoside transporter 3, hCNT3 (SLC28A3), arising from single nucleotide polymorphisms in coding regions of the hCNT3 gene.