SLC28A1 Antibodies

AND SLC28A1 ELISA kits, SLC28A1 Proteins

Many biological assays use antibodies to detect SLC28A1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC28A1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC28A1 antibodies...

We validate the specificity of these antibodies to SLC28A1 by testing them on tissues known to express SLC28A1 positively and negatively. Browse below to find the SLC28A1 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC28A1 Infographic by Boster Bio

All SLC28A1 Products

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Specificity

Applications

Price

Anti-SLC28A1 Antibody

Human, Mouse, Rat

$405
Cat # A07421
100ul

SLC28A1 (NM_004213) Human Over-expression Lysate

Human

$960
Cat # LS009154
100 µg

SLC28A1 Overview

Facts about Sodium/nucleoside cotransporter 1.

SLC28A1 3D structure. Source: alphafold

Sodium/nucleoside cotransporter 1 (SLC28A1)

Sodium-dependent and pyrimidine-selective.
Exhibits the transport characteristics of the nucleoside transport system cit or N2 subtype (N2/cit) (selective for pyrimidine nucleosides and adenosine).

Additionally, it transports the antiviral pyrimidine nucleoside analogs 3'-azido-3'-deoxythymidine (AZT) and 2',3'-dideoxycytidine (ddC). It can be involved in the intestinal absorption and renal handling of pyrimidine nucleoside analogs used to treat acquired immunodeficiency syndrome (AIDS).

Gene Information

Human
Gene Name:	SLC28A1
Uniprot:	O00337
Entrez:	9154

Family

Belongs to:

concentrative nucleoside transporter (CNT) (TC 2.A.41) family

Alternative Names

CNT 1; CNT1HCNT1; Concentrative nucleoside transporter 1; hCNT1; Na(+)/nucleoside cotransporter 1; sodium/nucleoside cotransporter 1; Sodium-coupled nucleoside transporter 1; solute carrier family 28 (sodium-coupled nucleoside transporter), member 1; Solute carrier family 28 member 1

Molecular Weight

Mass (kDA):
71.584 kDA

Genomic Context


Human

Location:	15q25.3
Sequence:	15; NC_000015.10 (84884350..84975649)

Tissue Specificity

Expressed in kidney.

Subcellular Localizations

Cell membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Pancreas
Lipodystrophy
Solid Tumor
Diabetic Nephropathy
Malignant Neoplasm Of Breast
Congenital Dyserythropoietic Anemia
Diabetes Mellitus
Leukemia, Myelocytic, Acute
Malignant Childhood Neoplasm
Heart Diseases

Myeloid Leukemia
Diabetes Mellitus, Experimental
Hiv Infections
Cardiotoxicity
Leukemia
Pancreatic Neoplasm
Hyperglycemia

Pathways

Transport
Nucleoside Salvage
Localization
Translation
Cell Cycle
Nucleoside Transport
Intracellular Nucleoside Transport
Uridine Transport

Excretion
Secretion

PTMs

Glycoprotein

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC28A1

References

PMID: 9124315 by Ritzel M.W.L., et al. Molecular cloning and functional expression of cDNAs encoding a human Na+-nucleoside cotransporter (hCNT1).

PMID: 10455109 by Loewen S.K., et al. Identification of amino acid residues responsible for the pyrimidine and purine nucleoside specificities of human concentrative Na(+) nucleoside cotransporters hCNT1 and hCNT2.