SLC26A7 Antibodies

AND SLC26A7 ELISA kits, SLC26A7 Proteins

Many biological assays use antibodies to detect SLC26A7, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC26A7 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC26A7 antibodies...

We validate the specificity of these antibodies to SLC26A7 by testing them on tissues known to express SLC26A7 positively and negatively. Browse below to find the SLC26A7 antibody that suites your experiment. We have 0 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC26A7 Overview

Facts about Anion exchange transporter.

SLC26A7 3D structure. Source: alphafold

Anion exchange transporter (SLC26A7)

Acts as a sodium-independent DIDS-sensitive anion exchanger mediating bicarbonate, chloride, sulfate and oxalate transport. May play a role in the maintenance of the electrolyte and acid-base homeostasis in the kidney, by acting as a distal excretory segment-specific anion exchanger.

Plays a major role in gastric acid secretion. .

Gene Information

Human
Gene Name:	SLC26A7
Uniprot:	Q8TE54
Entrez:	115111

Family

Belongs to:

SLC26A/SulP transporter (TC 2.A.53) family

Alternative Names

MGC126268; solute carrier family 26, member 7; sulfate anion transporter

Molecular Weight

Mass (kDA):
72.213 kDA

Genomic Context


Human

Location:	8q21.3
Sequence:	8; NC_000008.11 (91209496..91398155)

Tissue Specificity

Expressed in tonsillar high endothelial venule endothelial cells (HEVEC), placenta and in testis, expressed in a subgroup of basal cells in the epididymal ducts.

Subcellular Localizations

Recycling endosome membrane; Multi-pass membrane protein. Expressed in the cytoplasm in recycling endosomes of medullary collecting duct cells and in acid-secreting gastric parietal cells. Targeted to the basolateral membrane in hypertonicity and potassium depletion.

Diseases

Disease Of Adrenal Medulla
Acidosis
Cystic Fibrosis
Kidney Calculi
Hyperoxaluria
Congenital Secretory Diarrhea, Chloride Type
Macule
Posterior Reversible Encephalopathy Syndrome
Metabolic Acidosis
Multicystic Dysplastic Kidney
Diastrophic Dysplasia
Dysplasia

Fibrosis
Deprivation Of Water
Malignant Neoplasms
Chimera Disorder
Diarrhea
Nephrolithiasis

Pathways

Transport
Secretion
Localization
Anion Transport
Acid Secretion
Sulfate Transport
Oxalate Transport
Bicarbonate Transport
Gastric Acid Secretion

Anion Homeostasis
Ion Transport
Cell Division
Excretion

PTMs

Sulphation

Research Areas

Lipid and Metabolism
Plasma Membrane Markers
Signal Transduction

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC26A7

References

PMID: 11829495 by Vincourt J.-B., et al. Molecular cloning of SLC26A7, a novel member of the SLC26 sulfate/anion transporter family, from high endothelial venules and kidney.

PMID: 11834742 by Lohi H., et al. Functional characterization of three novel tissue-specific anion exchangers SLC26A7, -A8, and -A9.