Prestin Antibodies

AND Slc26a5 ELISA kits, Prestin Proteins

Many biological assays use antibodies to detect Prestin, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Prestin in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Prestin antibodies...

We validate the specificity of these antibodies to Prestin by testing them on tissues known to express Slc26a5 positively and negatively. Browse below to find the Slc26a5 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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Slc26a5 Infographic by Boster Bio

All Slc26a5 Products

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Anti-Prestin SLC26A5 Antibody

Human, Mouse, Rat

IHC, WB

$380
Cat # A05925-1
100ul

SLC26A5 (NM_198999) Human Over-expression Lysate

Human

$960
Cat # LS375611
100 µg

Slc26a5 Overview

Facts about Prestin.

Prestin (Slc26a5)

Motor protein which converts auditory stimuli to length changes in outer hair cells and mediates sound amplification in the mammalian hearing organ. Prestin is a bidirectional voltage- to-force converter, it can operate at microsecond rates.

It utilizes cytoplasmic anions as extrinsic voltage detectors, probably chloride and bicarbonate. They move towards the extracellular surface after hyperpolarization, and towards the cytoplasmic side in response to depolarization.

Gene Information

Mouse
Gene Name:	Slc26a5
Uniprot:	Q99NH7
Entrez:	80979

Family

Belongs to:

SLC26A/SulP transporter (TC 2.A.53) family

Alternative Names

DFNB61PRESprestin (motor protein); MGC118886; MGC118887; MGC118888; MGC118889; prestin; Solute carrier family 26 member 5; solute carrier family 26, member 5 (prestin)

Molecular Weight

Mass (kDA):
81.337 kDA

Genomic Context


Mouse

Location:	5 A3\|5 9.97 cM
Sequence:	5;

Tissue Specificity

Expressed in the outer hair cells (OHC) of the organ of Corti of the inner ear. Also weak expression in brain and testis. Very weakly expressed in heart, spleen, muscle and lactating mammary glands.

Diseases

Posterior Reversible Encephalopathy Syndrome
Complete Hearing Loss
Sensorineural Hearing Loss (disorder)
Diarrhea
Pendred's Syndrome
Cystic Fibrosis
Deafness Congenital
Dysplasia
Diastrophic Dysplasia
Fibrosis
Edema
Hearing Problem

Hypothyroidism
Hereditary Diseases
Traditional Serrated Adenoma
Lymphoproliferative Disorder Of The Skin
Congenital Infectious Disease
Chondrodysplasia Punctata
Malnutrition

Pathways

Transport
Localization
Anion Transport
Excretion
Glycosylation
Ion Transport
Sulfate Transport
Fructose Transport
Antiport

Cell Motility
Water Transport
Cell Differentiation
Innervation

PTMs

Phosphorylation
Glycosylation

Dephosphorylation
Deglycosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/Slc26a5

References

PMID: 14553901 by Dougherty G.W., et al. Expression of prestin, a membrane motor protein, in the mammalian auditory and vestibular periphery.

PMID: 12584604 by Zheng J., et al. Genomic characterization and expression of mouse prestin, the motor protein of outer hair cells.