ADP/ATP translocase 1 Antibodies

AND SLC25A4 ELISA kits, ADP/ATP translocase 1 Proteins

Many biological assays use antibodies to detect ADP/ATP translocase 1, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with ADP/ATP translocase 1 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop ADP/ATP translocase 1 antibodies...

We validate the specificity of these antibodies to ADP/ATP translocase 1 by testing them on tissues known to express SLC25A4 positively and negatively. Browse below to find the SLC25A4 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC25A4 Infographic by Boster Bio

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Anti-ADP/ATP translocase 1 SLC25A4 Antibody

Human

IF, ICC, WB

$405
Cat # A03976
100ul

SLC25A4 (NM_001151) Human Over-expression Lysate

Human

$628
Cat # LS000291
100 µg

SLC25A4 Overview

Facts about ADP/ATP translocase 1.

SLC25A4 3D structure. Source: alphafold

ADP/ATP translocase 1 (SLC25A4)

Involved in mitochondrial ADP/ATP transport. Catalyzes the exchange of cytoplasmic ADP with mitochondrial ATP across the mitochondrial inner membrane.

Gene Information

Human
Gene Name:	SLC25A4
Uniprot:	P12235
Entrez:	291

Family

Belongs to:

mitochondrial carrier (TC 2.A.29) family

Alternative Names

AAC1; Adenine nucleotide translocator 1; ADP; ADP/ATP translocase 1; ANT 1; ANT1adenine nucleotide translocator 1 (skeletal muscle); ATP carrier protein 1; ATP carrier protein, heart/skeletal muscle isoform T1; ATP carrier protein, heart/skeletal muscle; heart/skeletal muscle ATP/ADP translocator; PEO2; PEO3; solute carrier family 25 (mitochondrial carrier; adenine nucleotidetranslocator), member 4; Solute carrier family 25 member 4; T1ANT

Molecular Weight

Mass (kDA):
33.064 kDA

Genomic Context


Human

Location:	4q35.1
Sequence:	4; NC_000004.12 (185143266..185150382)

Subcellular Localizations

Mitochondrion inner membrane; Multi-pass membrane protein.

Diseases

External Ophthalmoplegia
Ophthalmoplegia
Chronic Progressive External Ophthalmoplegia
Atrophy
Optic Atrophy
Ataxia
Mitochondrial Diseases
Myopathy
Complete Hearing Loss
Optic Atrophy, Autosomal Dominant
Neoplasm Metastasis
Polyneuropathy

Neuromuscular Diseases
Muscular Dystrophy, Facioscapulohumeral
Parkinson Disease
Misalignment
Edema
Malignant Neoplasms
Secondary Parkinson Disease

Interacting Proteins

LRRK2

Pathways

Localization
Mitochondrial Fusion
Notch Signaling Pathway
Male Meiosis
Cell Fate Determination
Pathogenesis
Meiosis
Glycolysis

Muscle Atrophy
Spermatogenesis

PTMs

Acetylation
Methylation

Phosphoprotein
S-nitrosylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC25A4

References

PMID: 2823266 by Neckelmann N., et al. cDNA sequence of a human skeletal muscle ADP/ATP translocator: lack of a leader peptide, divergence from a fibroblast translocator cDNA, and coevolution with mitochondrial DNA genes.

PMID: 2541251 by Cozens A.L., et al. DNA sequences of two expressed nuclear genes for human mitochondrial ADP/ATP translocase.