SLC22A3 Antibodies

AND SLC22A3 ELISA kits, SLC22A3 Proteins

Many biological assays use antibodies to detect SLC22A3, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with SLC22A3 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop SLC22A3 antibodies...

We validate the specificity of these antibodies to SLC22A3 by testing them on tissues known to express SLC22A3 positively and negatively. Browse below to find the SLC22A3 antibody that suites your experiment. We have 3 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC22A3 Infographic by Boster Bio

All SLC22A3 Products

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Product

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Specificity

Applications

Price

Anti-SLC22A3 (Q306) Antibody

Human, Mouse, Rat

$405
Cat # A04914
100ul

Anti-SLC22A3 Antibody Picoband®

Human, Mouse

Flow Cytometry, WB

$370
Cat # A04914-1
100 μg/vial

Anti-SLC22A3 Rabbit Monoclonal Antibody

Human

Flow Cytometry, IHC, WB

$370
Cat # M04914
100 μl/vial

SLC22A3 Overview

Facts about Solute carrier family 22 member 3.

SLC22A3 3D structure. Source: alphafold

Solute carrier family 22 member 3 (SLC22A3)

Mediates potential-dependent transport of many different organic cations. May play a substantial role in the disposition of cationic neurotoxins and neurotransmitters in the brain.

Gene Information

Human
Gene Name:	SLC22A3
Uniprot:	O75751
Entrez:	6581

Family

Belongs to:

major facilitator (TC 2.A.1) superfamily

Alternative Names

EMTEMTH; Extraneuronal monoamine transporter; OCT3EMT organic cation transporter 3; Organic cation transporter 3; solute carrier family 22 (extraneuronal monoamine transporter), member 3; solute carrier family 22 member 3

Molecular Weight

Mass (kDA):
61.28 kDA

Genomic Context


Human

Location:	6q25.3
Sequence:	6; NC_000006.12 (160348378..160454982)

Tissue Specificity

Expressed in placenta, skeletal muscle, prostate, aorta, liver, fetal lung, salivary gland, adrenal gland, kidney and brain cortex. No expression detected in spleen.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Malignant Neoplasm Of Prostate
Carcinoma
Diabetes Mellitus
Nervousness
Dysequilibrium Syndrome
Persistant Generalized Lymphadenopathy
Liver Carcinoma
Prostatic Neoplasms
Tumor Progression
Hypertensive Disease

Osteochondritis Dissecans
Anxiety Disorders
Malignant Paraganglionic Neoplasm
Mental Disorders
Colorectal Neoplasms
Gilles De La Tourette Syndrome
Diabetes Mellitus, Insulin-dependent

Interacting Proteins

ABL1

Pathways

Transport
Methylation
Cell Cycle
Dna Methylation
Localization
Pathogenesis
Cell Adhesion
Immune Response
Hypersensitivity
Muscle Contraction
Response To Vitamin
Response To Vitamin D
Intestinal Absorption

Cell Differentiation
Catecholamine Transport
Smooth Muscle Contraction
Signal Transmission
Energy Homeostasis
Histamine Uptake
Histamine Transport

PTMs

Methylation

Demethylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC22A3

References

PMID: 10196521 by Gruendemann D., et al. Molecular identification of the corticosterone-sensitive extraneuronal catecholamine transporter.

PMID: 9933568 by Verhaagh S., et al. Cloning of the mouse and human solute carrier 22a3 (Slc22a3/SLC22A3) identifies a conserved cluster of three organic cation transporters on mouse chromosome 17 and human 6q26-q27.