Thiamine transporter 2 Antibodies

AND SLC19A3 ELISA kits, Thiamine transporter 2 Proteins

Many biological assays use antibodies to detect Thiamine transporter 2, such as Western Blot (WB), ELISA, Flow Cytometry, Immunocytochemistry (IHC). These antibodies can be polyclonal or monoclonal, and react with Thiamine transporter 2 in Human, Mouse, Rat, and many other animal samples. Boster Bio use mainly mouse and rabbit to develop Thiamine transporter 2 antibodies...

We validate the specificity of these antibodies to Thiamine transporter 2 by testing them on tissues known to express SLC19A3 positively and negatively. Browse below to find the SLC19A3 antibody that suites your experiment. We have 2 of these antibodies and many publications and validation images.

If you cannot find antibodies that fit your needs, contact us for making custom antibodies. We have a full suite of custom antibody services covering from research to diagnostic and therapeutic applications.

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SLC19A3 Infographic by Boster Bio

All SLC19A3 Products

Product

Figures

Specificity

Applications

Price

SLC19A3 (NM_025243) Human Recombinant Protein

$1249
Cat # PROTQ9BZV2
20 µg

SLC19A3 (NM_025243) Human Over-expression Lysate

Human

$628
Cat # LS080704
100 µg

SLC19A3 Overview

Facts about Thiamine transporter 2.

SLC19A3 3D structure. Source: alphafold

Thiamine transporter 2 (SLC19A3)

Mediates high affinity thiamine uptake, probably by means of a proton anti-port mechanism. Has no folate transport action.

Gene Information

Human
Gene Name:	SLC19A3
Uniprot:	Q9BZV2
Entrez:	80704

Family

Belongs to:

reduced folate carrier (RFC) transporter (TC 2.A.48) family

Alternative Names

Solute carrier family 19 member 3; solute carrier family 19, member 3; thiamine transporter 2; THTR2; ThTr-2

Molecular Weight

Mass (kDA):
55.665 kDA

Genomic Context


Human

Location:	2q36.3
Sequence:	2; NC_000002.12 (227683763..227718030, complement)

Tissue Specificity

Widely expressed but most abundant in placenta, kidney and liver.

Subcellular Localizations

Membrane; Multi-pass membrane protein.

Diseases

Malignant Neoplasms
Neoplasms
Thiamine Deficiency
Malignant Neoplasm Of Breast
Mammary Neoplasms
Encephalopathies
Basal Ganglia Diseases
Anemia
Anemia, Megaloblastic
Thiamine-responsive Megaloblastic Anemia
Dystonia Disorders
Wernicke Encephalopathy

Stomach Neoplasms
Confusion
Carcinoma
Generalized Dystonia
Brain Injuries
Spasm
Diabetes Mellitus

Pathways

Transport
Thiamine Transport
Methylation
Dna Methylation
Localization
Intestinal Absorption
Histone Deacetylation
Meiosis Ii
Developmental Maturation
Spermatogenesis
Demethylation

Histone H3 Acetylation
Pathogenesis
Meiosis
Excretion
Secretion
Oncogenesis

PTMs

Methylation
Demethylation

Deacetylation
Acetylation

For details, visit:
bosterbio.com/bosterbio-gene-info-cards/SLC19A3

References

PMID: 11136550 by Eudy J.D., et al. Identification and characterization of the human and mouse SLC19A3 gene: a novel member of the reduced folate family of micronutrient transporter genes.

PMID: 11731220 by Rajgopal A., et al. SLC19A3 encodes a second thiamine transporter ThTr2.